Abstract Autism spectrum disorder (ASD) in children is a major public health challenge. The potential epidemiological links between heavy metal exposure and ASD remains a controversial issue. This critical review examines the epidemiological discrepancies, including variations in exposure assessment, study design, and population differences that ...
Aporajita Das Trisha +3 more
wiley +1 more source
Physiological and Behavioural Characterisation of a Novel Steroid Sulfatase‐Deficient Mouse
STS‐deficient mice are grossly healthy and breed as expected, but are mildly hyperactive and have heavier hearts compared with sex‐matched wildtype controls. ABSTRACT Steroid sulfatase (STS) cleaves sulphate groups from steroid hormones. In humans, STS deficiency is associated with X‐linked ichthyosis, an increased predisposition to neurodevelopmental ...
Trevor Humby +7 more
wiley +1 more source
Evolutionary constraints impose multiple checkpoints that block mammalian sensory hair cell regeneration. [PDF]
Zhang X, Su Z, Guan D, Liu X, Xie H.
europepmc +1 more source
Interindividual variability in static apnoea performance is partly explained by genetic factors
Abstract A large interindividual variability exists in maximal apnoea duration and the physiological adjustments that occur during apnoea. Although a few genes have been found to be associated with some of the cardiovascular responses during apnoea, the extent to which genetic and environmental factors contribute to individual differences in apnoea ...
Anastasios Makris +5 more
wiley +1 more source
Advances in pathogenesis, novel therapeutic strategies and interventions for age-related hearing loss. [PDF]
Wen Z +6 more
europepmc +1 more source
Abstract Muscle contraction increases motor evoked potential (MEP) amplitude, decreasing motor threshold (MT). Correspondingly, trials where baseline EMG amplitude exceeds a specified threshold are often rejected. We aimed to investigate the influence of motor activity below such a threshold of MEP amplitude.
Séamus O'Sullivan +10 more
wiley +1 more source
A Fungal-Derived Bioactive Resource for Cochlear Protection: <i>Sanghuangporus sanghuang</i> Extract Mitigates Acoustic Trauma through Nrf2/HO-1 Antioxidant Axis. [PDF]
Lee H, Lee C, Kim YT, Park J, Lee J.
europepmc +1 more source
TrkB activation mitigates blast-induced cochlear pathology and promotes auditory recovery in a compressed-air blast model. [PDF]
Bae HG +5 more
europepmc +1 more source
HSD17B7 is required for the function of sensory hair cells by regulating cholesterol synthesis. [PDF]
Shen Y +7 more
europepmc +1 more source

