Results 191 to 200 of about 282,949 (249)

Pebbled mosaic‐like heterogeneous echogenicity in ovarian immature teratomas and correlation of ultrasound patterns with pathological grades

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
This study characterizes heterogeneous mottled grayscale ultrasound echoes of ovarian immature teratoma as the “pebbled mosaic sign,” noting solid lesions correlate with advanced pathological grades. Preoperative identification of immature tissue informs operative stratification. Abstract Introduction Ovarian immature teratomas (ITs) are rare malignant
Tianyu Zhang   +7 more
wiley   +1 more source

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub   +2 more
wiley   +1 more source

Hair Degradation Patterns in Aquatic and Soil Environments

open access: yesArchaeometry, EarlyView.
ABSTRACT Hair is a biological material that can provide information in archaeology and forensics. Previous studies have mainly examined changes occurring post‐mortem. In this study, we focused on hair pulled out ante‐mortem. The aim of the study was to identify patterns in the degradation of hair in water and soil.
Katarzyna Palacz‐Ziółek   +3 more
wiley   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle   +9 more
wiley   +1 more source

Disruption of microtubules with low intensity ultrasound rescues hair follicle damage by paclitaxel in mouse models. [PDF]

open access: yesNat Commun
Amaya C   +7 more
europepmc   +1 more source

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