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The hair follicle—a stem cell zoo
Experimental Cell Research, 2010Recent studies on stem cells in the adult hair follicle (HF) have uncovered a veritable menagerie of exceptionally diverse and dynamic keratinocytes with stem cell properties located in distinct regions of the HF. Although endowed with specific functions during normal hair follicle maintenance, the majority of these cells can act as multipotent stem ...
Viljar, Jaks +2 more
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Unveiling Hair Follicle Stem Cells
Stem Cell Reviews and Reports, 2010Adult mammalian skin consists of the epidermis, hair follicles (HFs), and sebaceous glands (SGs). Each of these three epithelial lineages contains its own stem cell (SC) population for normal tissue homeostasis, HF cycling, and repair of the epidermis following injury.
Leilei, Yang, Ruiyun, Peng
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Hair follicle stem cells feel the pressure
Cell Stem Cell, 2022The number of hair follicle stem cells decreases during aging and in hair-loss disorders, such as alopecia. In this issue of Cell Stem Cell, Xie et al. (2021) discover that the hair shaft serves as a physical niche component for the preservation of hair follicle stem cells.
Taylor, Hinnant, Terry, Lechler
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Hair Follicle Stem Cells for Tissue Regeneration
Tissue Engineering Part B: Reviews, 2022With the positive outcomes of various cell therapies currently under preclinical and clinical studies, there is a significant interest in novel stem cell sources with unique therapeutic properties. Studies over the past two decades or so demonstrated the feasibility to isolate multipotent/pluripotent stem cells from hair follicles.
Alyssa, Peterson, Lakshmi S, Nair
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2011
The cyclic renewal of hair follicles offers an exclusive opportunity to study stem cells behaviors, that is their contributions and mode of maintenance. The hair follicle renewal comprises a growth phase of morphogenesis and elongation that is interrupted by a phase of massive apoptosis followed by a resting phase.
Emilie Legué +2 more
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The cyclic renewal of hair follicles offers an exclusive opportunity to study stem cells behaviors, that is their contributions and mode of maintenance. The hair follicle renewal comprises a growth phase of morphogenesis and elongation that is interrupted by a phase of massive apoptosis followed by a resting phase.
Emilie Legué +2 more
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Identification and Characterization of Hair Follicle Stem Cells
2018Hair follicle stem cells (HFSCs) are epithelial cells that inhabit in the bulge region of hair follicles. They govern development of hair follicle as well as periodically regeneration of hair follicle. Under special condition, they also play roles in homeostasis of skin and other skin appendages.
Xiaoyang, Wang, Yizhan, Xing, Yuhong, Li
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Gene and Stem Cell Therapy of the Hair Follicle
2004The hair follicle is a highly complex appendage of the skin containing a multiplicity of cell types. The follicle undergoes constant cycling through the life of the organism including growth and resorption with growth dependent on specific stem cells.
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Clinical calcium, 2017
The hair follicle is a complex miniorgan of the skin and undergoes cycles of growth(anagen), apoptosis-mediated regression(catagen)and rest(telogen). Regeneration of the new hair shaft dependent on the activation of hair follicle stem cells(HFSCs), harboured in the bulge region.
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The hair follicle is a complex miniorgan of the skin and undergoes cycles of growth(anagen), apoptosis-mediated regression(catagen)and rest(telogen). Regeneration of the new hair shaft dependent on the activation of hair follicle stem cells(HFSCs), harboured in the bulge region.
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Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
EMBO Journal, 2021Tudorita Tumbar, Kefei Nina Li
exaly