Results 11 to 20 of about 601,255 (232)

Sensory hair cell death and regeneration in fishes [PDF]

Frontiers in Cellular Neuroscience, 2015
Sensory hair cells are specialized mechanotransductive receptors required for hearing and vestibular function. Loss of hair cells in humans and other mammals is permanent and causes reduced hearing and balance.
Jerry D. Monroe, Gopinath eRajadinakaran, Michael E. Smith   +2 more
doaj   +2 more sources

Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration. [PDF]

PLoS ONE, 2016
Unlike mammals, the non-mammalian vertebrate inner ear can regenerate the sensory cells, hair cells, either spontaneously or through induction after hair cell loss, leading to hearing recovery.
Sang Goo Lee, Mingqian Huang, Nikolaus D Obholzer, Shan Sun, Wenyan Li, Marco Petrillo, Pu Dai, Yi Zhou, Douglas A Cotanche, Sean G Megason, Huawei Li, Zheng-Yi Chen   +11 more
doaj   +1 more source

A Disulfide-Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self-Assembly Mechanism to Functional Application in Hair Regeneration. [PDF]

Adv Sci (Weinh)
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Wang L, Yang J, Jiang X, Zheng Z, Wei H, Li N, Chu X, Liu W.   +7 more
europepmc   +2 more sources

Exosomes and Hair Regeneration: A Systematic Review of Clinical Evidence Across Alopecia Types and Exosome Sources. [PDF]

Clin Cosmet Investig Dermatol
Mohammed A Al Ameer,1 Abdulaziz T Alnajim,1 Ali Al Ameer,2 Zainab Alsalman,3 Ghadeer A Al Ameer,4 Sarah T Alnajim,5 Anwar A Alghamdi,1 Raniya Moideen,4 Enas M Al Hadi6 1Department of Dermatology, Aseer Central Hospital, Abha, Saudi Arabia; 2Department of
Al Ameer MA, Alnajim AT, Al Ameer A, Alsalman Z, Al Ameer GA, Alnajim ST, Alghamdi AA, Moideen R, Al Hadi EM.   +8 more
europepmc   +2 more sources

Transcription Factor Reprogramming in the Inner Ear: Turning on Cell Fate Switches to Regenerate Sensory Hair Cells

Frontiers in Cellular Neuroscience, 2021
Non-mammalian vertebrates can restore their auditory and vestibular hair cells naturally by triggering the regeneration of adjacent supporting cells. The transcription factor ATOH1 is a key regulator of hair cell development and regeneration in the inner
Amrita A. Iyer, Amrita A. Iyer, Andrew K. Groves, Andrew K. Groves, Andrew K. Groves   +4 more
doaj   +1 more source

An ex vivo comparison of the tensile strengthening properties of protein derivatives on damaged hair [PDF]

, 2015
Conventional conditioning agents, cationic surfactants and polymers, are often limited in their ability to repair and strengthen the hair fibre, while protein-derived actives have been found to enhance the tensile strength of damaged hair.
Daniels, Gabriela, Grant-Ross, Peter, Nicholson, Sherine, Tamburic, Slobodanka   +3 more
core   +5 more sources

Advances in the study of hair follicle mesenchymal stem cells

Pifu-xingbing zhenliaoxue zazhi, 2022
Hair follicle mesenchymal stem cells (HFMSCs) are slow cycling label retaining cells with self-regeneration ability, high proliferative potential, and multi-directional differentiation.
Huijun LAI, Lan YANG, Furong YOU, Pingping MA, Hongwei GUO   +4 more
doaj   +1 more source

Characterizing human vestibular sensory epithelia for experimental studies: new hair bundles on old tissue and implications for therapeutic interventions in ageing. [PDF]

, 2015
Balance disequilibrium is a significant contributor to falls in the elderly. The most common cause of balance dysfunction is loss of sensory cells from the vestibular sensory epithelia of the inner ear.
Daniel J. Jagger, Axon, Patrick, Moffatt, D, Moffatt, David, Jagger, DJ, Tysome, James, Monksfield, Peter, Taylor, Ruth R., Jagger, Daniel J., Peter Monksfield, Donnelly, N, Lloyd, SK, Coulson, Chris, Irving, R, Coulson, C, Freeman, SR, Saeed, Shakeel R., Richard Irving, Simon K. Lloyd, Lloyd, Simon K., Forge, Andrew, Neil Donnelly, Freeman, Simon R., Shakeel R. Saeed, Taylor, RR, David Moffatt, Forge, A, Irving, Richard, Saeed, SR, Axon, P, Ruth R. Taylor, Monksfield, P, Simon R. Freeman, Donnelly, Neil, Chris Coulson, Tysome, J, Andrew Forge, Patrick Axon, James Tysome   +38 more
core   +1 more source

Basic principles of hair follicle structure, morphogenesis, and regeneration

, 2023
Diseases affecting the hair follicle are common in domestic animals, but despite the importance of an intact skin barrier and a fully functional hair coat, knowledge about the detailed morphological features and the diversity of these complex mini-organs
Welle, Monika M, Monika M. Welle
core   +1 more source

Suppression of Inflammation Delays Hair Cell Regeneration and Functional Recovery Following Lateral Line Damage in Zebrafish Larvae

Biomolecules, 2020
Cochlear hair cells in human beings cannot regenerate after loss; however, those in fish and other lower species can. Recently, the role of inflammation in hair cell regeneration has been attracting the attention of scientists.
Ru Zhang, Xiaopeng Liu, Yajuan Li, Ming Wang, Lin Chen, Bing Hu   +5 more
doaj   +1 more source