Results 21 to 30 of about 601,255 (232)

Proliferative regeneration of zebrafish lateral line hair cells after different ototoxic insults.

PLoS ONE, 2012
Sensory hair cells in the zebrafish lateral line regenerate rapidly and completely after damage. Previous studies have used a variety of ototoxins to kill lateral line hair cells to study different phenomena including mechanisms of hair cell death and ...
Scott M Mackenzie, David W Raible
doaj   +1 more source

Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles [PDF]

PeerJ, 2019
Secreted Frizzled-related Protein 4 (sFRP4) belongs to Wnt inhibitors. Previously, we reported that sFRP4 inhibited the differentiation of melanocyte.
Haiying Guo, Yizhan Xing, Fang Deng, Ke Yang, Yuhong Li   +4 more
doaj   +2 more sources

The role of epigenetic modifications in sensory hair cell development, survival, and regulation

Frontiers in Cellular Neuroscience, 2023
The cochlea is the sensory organ in the periphery, and hair cells are its main sensory cells. The development and survival of hair cells are highly controlled processes.
Ying Xiao, Dan Li
doaj   +1 more source

Crosstalk between endothelial cells and dermal papilla entails hair regeneration and angiogenesis during aging [PDF]

Journal of Advanced Research
Siyi Zhou, Cheng-Ming Chuong, Xiao Xiang
exaly   +2 more sources

Wound Induced Hair Neogenesis – A Novel Paradigm for Studying Regeneration and Aging

Frontiers in Cell and Developmental Biology, 2020
Hair follicles are the signature dermal appendage of mammals. They can be thought of as mini-organs with defined polarity, distinct constituent cell types, dedicated neurovascular supply, and specific stem cell compartments. Strikingly, some mammals show
Myan Bhoopalam, Luis A. Garza, Sashank K. Reddy   +2 more
doaj   +1 more source

Prolactin delays hair regrowth in mice [PDF]

, 2006
Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting that prolactin has a role in ...
Ashby, M.G., Nixon, A.J., Pearson, A.J., Ormandy, C.J., Blazek, K., Wilkins, Richard J., Craven, A.J.   +6 more
core   +1 more source

Augmenting endogenous wnt signaling improves skin wound healing [PDF]

, 2013
Wnt signaling is required for both the development and homeostasis of the skin, yet its contribution to skin wound repair remains controversial. By employing Axin2(LacZ/+) reporter mice we evaluated the spatial and temporal distribution patterns of Wnt ...
Manzano Wilfred R., Fang Mark Y., Girija R Dhamdhere, Anthony E. Oro, Bo Liu, Fang, Mark Y, Whyte, Jemima L., Helms Jill A., Wilfred R. Manzano, Nick D. Evans (474290), Manzano, Wilfred R, Howard Y. Chang (215450), Smith, Andrew A, Manzano, Wilfred R., Whyte, Jemima L, Jemima L. Whyte (474287), Nick D Evans, Helms, Jill A., Andrew A Smith, Anthony E Oro, Andrew A. Smith (474288), Oro Anthony E., Chang, Howard Y., Jemima L Whyte, Liu Bo, Howard Y Chang, Dhamdhere, Girija R, Evans Nick D., Evans, Nick D., Wilfred R. Manzano (474289), Oro, Anthony E., Nick D. Evans¤a, Smith Andrew A., Whyte Jemima L., Liu, Bo, Mark Y. Fang (474292), Wilfred R Manzano, Jill A. Helms (25398), Fang, Mark Y., Smith, Andrew A., Andrew A. Smith, Evans, Nick D, Helms, Jill A, Girija R. Dhamdhere (474291), Girija R. Dhamdhere, Jill A Helms, Mark Y. Fang¤b, Anthony E. Oro (474293), Jill A. Helms, Dhamdhere, Girija R., Mark Y Fang, Chang, Howard Y, Chang Howard Y., Jemima L. Whyte, Oro, Anthony E, Howard Y. Chang, Bo Liu (127343), Dhamdhere Girija R.   +57 more
core   +2 more sources

Hearing Recovery Induced by DNA Demethylation in a Chemically Deafened Adult Mouse Model

Frontiers in Cellular Neuroscience, 2022
Functional hair cell regeneration in the adult mammalian inner ear remains challenging. This study aimed to study the function of new hair cells induced by a DNA demethylating agent 5-azacytidine.
Xin Deng, Zhengqing Hu, Zhengqing Hu
doaj   +1 more source

Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration

Chinese Medicine, 2023
Background As a supplement for promoting hair health, Shi-Bi-Man (SBM) is a prescription comprising various traditional Chinese medicines. Though SBM has been reported to promote hair regeneration, its molecular mechanism remains unclear.
Haojie Du, Tao Zhang, Qiao Wang, Xinran Cao, Huiwen Zheng, Jiabin Li, Jianxia Zhu, Jiao Qu, Lehang Guo, Yang Sun   +9 more
doaj   +1 more source

Editorial: Sensory Hair Cell Death and Regeneration [PDF]

, 2016
Sensory hair cells are the specialized mechanosensory receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance.
Michael E. Smith, Allison B. Coffin, Allison B Coffin, Andrew K. Groves, Andy Groves   +4 more
core   +1 more source