Results 171 to 180 of about 46,260 (298)

Chitosan nanoparticles as a strategy for enhancing h6h gene expression and tropane alkaloid production in Hyoscyamus reticulatus hairy roots. [PDF]

Sci Rep
Godsi R, Hosseini B, Hedayati A.
europepmc   +1 more source

Brain‐Adhesive Bioelectronics With Shape‐Morphable and Biodegradable Properties for Stable Brain Signal Monitoring

Advanced Science, EarlyView.
A brain‐adhesive sensor (B‐Sensor) was developed by integrating a self‐healing biodegradable elastomer, a tissue‐adhesive hydrogel, and molybdenum electrodes. The B‐Sensor adheres to brain tissue, conforms to cortical curvatures, and maintains stable electrical performance over the intended period for reliable recording of spatiotemporal brain activity
Heewon Choi, Soeun Kim, Sumin Kim, Jaehyun Park, Soojung An, Sungjun Yoon, Mikyung Shin, Sangho Cho, Donghee Son   +8 more
wiley   +1 more source

Plant hairy roots for the production of extracellular vesicles with antitumor bioactivity. [PDF]

Commun Biol, 2022
Boccia E, Alfieri M, Belvedere R, Santoro V, Colella M, Del Gaudio P, Moros M, Dal Piaz F, Petrella A, Leone A, Ambrosone A.   +10 more
europepmc   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Rosmarinic Acid Synthase 1 Phosphorylation by SmMAPK3 Is Required for Salicylic Acid-Induced Salvianolic Acid Accumulation in Salvia miltiorrhiza Hairy Roots. [PDF]

Plant Biotechnol J
Yin X, Liu S, Zhang Y, Yang W, Bu J, Zhang B, Dong J.   +6 more
europepmc   +1 more source

The SmNPR4-SmTGA5 module regulates SA-mediated phenolic acid biosynthesis in Salvia miltiorrhiza hairy roots. [PDF]

Hortic Res, 2023
Ding M, Zhang B, Zhang S, Hao R, Xia Y, Ma P, Dong J.   +6 more
europepmc   +1 more source

An Intelligent Magneto‐Mechanical Platform for Cellular Sensing in 3D Microenvironments

Advanced Science, EarlyView.
This study presents MagMI, a pioneering machine intelligence‐driven magneto‐mechanical sensing platform. It utilizes magneto‐mechanical arrays and machine learning to achieve label‐free, real‐time monitoring and classification of cellular proliferation dynamics within 3D microenvironments.
Yue Quan, Yuxin Wang, Sen Ding, Bingpu Zhou, Yinning Zhou   +4 more
wiley   +1 more source

Unraveling Paracetamol Metabolism and Its Circadian Regulation: Insights from Tobacco Hairy Roots as a Model System. [PDF]

Plants (Basel)
Sosa Alderete LG, Vezza M, Ibañez SG, Schroeder P, Agostini E, Talano MA.   +5 more
europepmc   +1 more source

Linum lewisii Adventitious and Hairy-Roots Cultures as Lignan Plant Factories. [PDF]

Antioxidants (Basel), 2022
Dougué Kentsop RA, Consonni R, Alfieri M, Laura M, Ottolina G, Mascheretti I, Mattana M.   +6 more
europepmc   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source