Results 1 to 10 of about 8,886,396 (384)

Protostellar half-life: new methodology and estimates [PDF]

A&A 618, A158 (2018), 2018
(Abridged) Protostellar systems evolve from prestellar cores, through the deeply embedded stage and then disk-dominated stage, before they end up on the main sequence. Knowing how much time a system spends in each stage is crucial for understanding how stars and associated planetary systems form, because a key constraint is the time available to form ...
L. Kristensen, M. Dunham
arxiv   +5 more sources

The αSynuclein half-life conundrum

Neurobiology of Disease
αSynuclein (αSyn) misfolding and aggregation frequently precedes neuronal loss associated with Parkinson's Disease (PD) and other Synucleinopathies. The progressive buildup of pathological αSyn species results from alterations on αSyn gene and protein ...
Anna Masato, Luigi Bubacco
doaj   +4 more sources

The half‐life of amitriptyline. [PDF]

British Journal of Clinical Pharmacology, 1978
HJ Rogers, PJ Morrison, ID Bradbrook
openalex   +5 more sources

Toxicity, Half-Life and Antitumor Activity of Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates as Novel Antimitotic CYP1A1-Targeted Prodrugs in Female Mouse Models [PDF]

Pharmaceutics
Background/Objectives: Chemoresistance of breast cancers (BCs) is a major impediment to current chemotherapeutics that urges the development of new drugs and new therapeutic approaches.
Atziri Corin Chavez Alvarez, Chahrazed Bouzriba, Vincent Ouellette, Mathieu Gagné-Boulet, Alexandre Patenaude, Sylvie Pilote, René C.-Gaudreault, Chantale Simard, Sébastien Fortin   +8 more
doaj   +2 more sources

nEXO: neutrinoless double beta decay search beyond 1028 year half-life sensitivity [PDF]

Journal of Physics G: Nuclear and Particle Physics, 2021
The nEXO neutrinoless double beta (0νββ) decay experiment is designed to use a time projection chamber and 5000 kg of isotopically enriched liquid xenon to search for the decay in 136Xe.
G. Adhikari, S. Al Kharusi, E. Angelico, G. Anton, I. Arnquist, I. Badhrees, J. Bane, V. Belov, E. Bernard, T. Bhatta, A. Bolotnikov, P. Breur, J. Brodsky, E. Brown, T. Brunner, E. Caden, G. Cao, L. Cao, C. Chambers, B. Chana, S. Charlebois, D. Chernyak, M. Chiu, B. Cleveland, R. Collister, S. Czyz, J. Dalmasson, T. Daniels, L. Darroch, R. DeVoe, M. L. di Vacri, J. Dilling, Y. Ding, A. Dolgolenko, M. Dolinski, A. Dragone, J. Echevers, M. Elbeltagi, L. Fabris, D. Fairbank, W. Fairbank, J. Farine, S. Ferrara, S. Feyzbakhsh, Y. Fu, G. Gallina, P. Gautam, G. Giacomini, W. Gillis, C. Gingras, D. Goeldi, R. Gornea, G. Gratta, C. Hardy, K. Harouaka, M. Heffner, E. Hoppe, A. House, A. Iverson, A. Jamil, M. Jewell, X. Jiang, A. Karelin, L. Kaufman, I. Kotov, R. Krücken, A. Kuchenkov, K. Kumar, Y. Lan, A. Larson, K. Leach, B. Lenardo, D. Leonard, G. Li, S. Li, Z. Li, C. Licciardi, R. Lindsay, R. Maclellan, M. Mahtab, P. Martel-Dion, J. Masbou, N. Massacret, T. McElroy, K. McMichael, M. Peregrina, T. Michel, B. Mong, D. Moore, K. Murray, J. Nattress, C. Natzke, R. J. Newby, K. Ni, F. Nolet, O. Nusair, J. Ondze, K. Odgers, A. Odian, J. Orrell, G. S. Ortega, C. Overman, S. Parent, A. Perna, A. Piepke, A. Pocar, J. Pratte, N. Priel, V. Radeka, E. Raguzin, G. J. Ramonnye, T. Rao, H. Rasiwala, S. Rescia, F. Retière, J. Ringuette, V. Riot, T. Rossignol, P. Rowson, N. Roy, R. Saldanha, S. Sangiorgio, X. Shang, A. Soma, F. Spadoni, V. Stekhanov, X. Sun, M. Tarka, S. Thibado, A. Tidball, J. Todd, T. Totev, S. Triambak, R. Tsang, T. Tsang, F. Vachon, V. Veeraraghavan, S. Viel, C. Vivo-Vilches, P. Vogel, J. Vuilleumier, M. Wagenpfeil, T. Wager, M. Walent, K. Wamba, Q. Wang, W. Wei, L. Wen, U. Wichoski, S. Wilde, M. Worcester, S. Wu, W. Wu, X. Wu, Q. Xia, W. Yan, H. Yang, L. Yang, O. Zeldovich, J. Zhao, T. Ziegler   +160 more
semanticscholar   +1 more source

Precise Half-Life Values for Two-Neutrino Double-β Decay: 2020 Review [PDF]

Universe, 2020
All existing positive results on two-neutrino double beta decay and two-neutrino double electron capture in different nuclei have been analyzed. Weighted average and recommended half-life values for 48Ca, 76Ge, 82Se, 96Zr, 100Mo, 100Mo - 100Ru (01 ...
A. Barabash
semanticscholar   +1 more source

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in non-human primates and has an extended half-life in humans

Science Translational Medicine, 2022
Despite the success of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, there remains a need for more prevention and treatment options for individuals remaining at risk of coronavirus disease 2019 (COVID-19).
Y. Loo, P. McTamney, R. Arends, M. Abram, A. Aksyuk, S. Diallo, D. J. Flores, E. Kelly, K. Ren, R. Roque, K. Rosenthal, K. Streicher, K. Tuffy, N. Bond, O. Cornwell, J. Bouquet, Li Cheng, J. Dunyak, Yue Huang, A. Rosenbaum, Venkatesh Pilla Reddy, H. Andersen, R. Carnahan, J. Crowe, A. Kuehne, A. Herbert, J. Dye, H. Bright, N. Kallewaard, M. Pangalos, M. Esser   +30 more
semanticscholar   +1 more source

Estimated half-life of SARS-CoV-2 anti-spike antibodies more than double the half-life of anti-nucleocapsid antibodies in healthcare workers

Clinical Infectious Diseases, 2021
two samples for each patient. The results were normally distributed for anti-S and anti-N (Shapiro-Wilk test) and the estimated mean half-life was 74.8 days [CI: 70.1-80.1] for anti-N and 197.2 days [CI: 172.4-230.4] for anti-S.
Jan Van Elslande, Lien Gruwier, L. Godderis, P. Vermeersch   +3 more
semanticscholar   +1 more source

The half-life of 129I [PDF]

Applied Radiation and Isotopes, 2018
The radionuclide 129I is a long-lived fission product that decays to 129Xe by beta-particle emission. It is an important tracer in geological and biological processes and is considered one of the most important radionuclides to be assessed in studies of global circulation. It is also one of the major contributors to radiation dose from nuclear waste in
Eduardo García-Toraño, Timotheos Altzitzoglou, Pavel Auerbach, Marie-Martine Bé, Christophe Bobin, Philippe Cassette, Frédéric Chartier, Rainer Dersch, Marta Fernández, Hélène Isnard, Karsten Kossert, Valérie Lourenço, Ole Nähle, Anthony Nonell, Virginia Peyrés, Stefaan Pommé, Andrej Rozkov, Anabel Sánchez-Cabezudo, Jana Sochorová   +18 more
openaire   +6 more sources

DEVELOPMENT OF DELIVERY SYSTEM FOR TRANSFERRIN USING CHEMICAL MODIFICATION APPROACH [PDF]

Basrah Journal of Veterinary Research, 2012
Proteins are very important molecules as therapeutics. They have several advantages over small molecule drugs but their use is limited by their circulation short half life, immunogenicity and physicochemical instability.
Athmar D. Habeeb
doaj   +1 more source