Results 61 to 70 of about 8,886,396 (384)
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Precise half-life measurement of the 10 h isomer in 154Tb
, 2009 The precise knowledge of the half-life of the reaction product is of crucial importance for a nuclear reaction cross section measurement carried out with the activation technique.
Berkes +18 more
core +1 more source
Defining extended half‐life rFVIII—A critical review of the evidence
Haemophilia, 2018 Recent haemophilia treatment advances include new recombinant FVIII (rFVIII) products with improved pharmacokinetic (PK) properties that aim to reduce the burden of prophylaxis.
J. Mahlangu +5 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
TspanC8 tetraspanins differentially regulate ADAM10 endocytosis and half-life
Life Science Alliance, 2019 This study demonstrates that the tetraspanins Tspan5 and Tspan15 which directly associate with the metalloprotease ADAM10 have an opposite impact on its endocytosis and half-life.
E. Eschenbrenner +8 more
semanticscholar +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
The half-life of $^{221}$Fr in Si and Au at 4K and at mK temperatures
, 2010 The half-life of the $\alpha$ decaying nucleus $^{221}$Fr was determined in different environments, i.e. embedded in Si at 4 K, and embedded in Au at 4 K and about 20 mK. No differences in half-life for these different conditions were observed within 0.1%
Breitenfeldt, M. +12 more
core +1 more source
Chemical Identification of the Radioelements Produced from Carbon and Boron by Deuteron Bombardment [PDF]
, 1935 Chemical experiments were made on the radioactive substances resulting from the bombardment of carbon and boron by deuterons. Carbon is shown to yield an isotope of nitrogen and boron an isotope of carbon.
Ridenour, L. N. +2 more
core +1 more source
Frontiers in Environmental Science, 2022 Crude oil contamination of soil and water resources is a widespread issue. The present study evaluated the degradation of aliphatic hydrocarbons (C11–C36) in crude oil by 17 bacteria isolated from a crude oil–contaminated soil. The results suggested that
Ashish Khandelwal +8 more
doaj +1 more source
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source