Results 61 to 70 of about 11,587 (189)

Neurophysiological Characteristics of Nitrous Oxide‐Induced Polyneuropathy: A Case Series

Journal of the Peripheral Nervous System, Volume 31, Issue 3, September 2026.
ABSTRACT Background Nitrous oxide (N2O) misuse is a growing health concern, with N2O‐induced neurological disorders increasingly reported across Europe. Among these, N2O‐induced polyneuropathy (PNP) can lead to permanent deficits, yet its neurophysiological characteristics remain inconsistently described.
Tanya Elisabeth Bentley, Volker Limmroth, Maximilian Zimmermann, Johannes Fabian Holle   +3 more
wiley   +1 more source

Clinical and Prognostic Findings in Psychotropic Substance Poisoning: A Cross-sectional Study [PDF]

Pharmaceutical and Biomedical Research
Background: Psychotropic substance poisoning is a growing public health concern.  Objectives: This study aimed to investigate patients with psychedelic poisoning and evaluate the frequency of clinical, preclinical, and prognostic findings.
Hanieh Hatampour, Hamid Reza Jamshidi, Komeil Aghazadeh-Habashi, Sareh Rafatmagham, Farhad Farnaghi, Hamidreza Ghasemirad, Mehrnoush Giahi Yazdi, Mohsen Jabari, Khashayar Moravej, Hamid Owliaey   +9 more
doaj  

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

Drug Testing and Analysis, Volume 18, Issue 8, Page 1036-1053, August 2026.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler, Tobias Veit, Thomas Keller, Volker Auwärter   +3 more
wiley   +1 more source

Opioid use disorder: current trends and potential treatments

Frontiers in Public Health
Opioid use disorder (OUD) is a major public health threat, contributing to morbidity and mortality from addiction, overdose, and related medical conditions. Despite our increasing knowledge about the pathophysiology and existing medical treatments of OUD,
Yu Kyung Lee, Mark S. Gold, Kenneth Blum, Panayotis K. Thanos, Colin Hanna, Brian S. Fuehrlein   +5 more
doaj   +1 more source

Leveraging Administrative Health Data to Capture Rare Adverse Drug Reactions: Identifying Pediatric Patients With Trimethoprim‐Sulfamethoxazole Acute Respiratory Distress Syndrome

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Rare adverse drug reactions (ADRs) are underrecognized and underreported in the electronic medical record (EMR). These events often require clinical review, making systematic identification challenging. The study aim was to develop an approach to prioritize identification and validation of a rare ADR to trimethoprim‐sulfamethoxazole causing ...
Keith Feldman, Jenna O. Miller, Katherine Doane, Laura Loftis, James W. Antoon, Kevin J. Downes, Jennifer L. Goldman   +6 more
wiley   +1 more source

Psychedelic Fauna for Psychonaut Hunters: A Mini-Review

Frontiers in Psychiatry, 2018
Currently different classes of psychoactive substances are easily available for abuse, including several hundred novel psychoactive substances (NPS).
Laura Orsolini, Laura Orsolini, Laura Orsolini, Michela Ciccarese, Duccio Papanti, Domenico De Berardis, Domenico De Berardis, Domenico De Berardis, Amira Guirguis, John M. Corkery, Fabrizio Schifano   +10 more
doaj   +1 more source

Synthesis of N‐Benzyl o‐Methoxy Phase I Metabolites for Use as Liquid Chromatography‐Quadrupole Time of Flight Standards

ChemistrySelect, Volume 11, Issue 30, 10 August 2026.
A novel synthetic method for three phase I o‐desmethyl NBOMe metabolites bromo‐ (3a) and iodo‐ (13b) and chloro‐ analogue (13c) was developed. LC‐QToF analysis confirmed that the synthetic standards matched the major peaks observed in urine sample screens for each of the respective halogen‐substituted metabolites indicating that the synthesised ...
Jordan Spangler, Martin R. Johnston, Peter Stockham   +2 more
wiley   +1 more source

The association between sleep disturbance and stimulant use: A cross‐lagged examination

Addiction, Volume 121, Issue 8, Page 2116-2126, August 2026.
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian, Renae D. Schmidt, Daniel J. Feaster, Rui Duan, Sophia T. Gonzalez, Kathryn Hefner, Dikla Shmueli‐Blumberg, Ashley Vena, Landhing M. Moran, Chloe A. DiCamillo, Shirin Shafazand, Susan Tross, Judith Feinberg   +12 more
wiley   +1 more source

When good times go bad: managing ‘legal high’ complications in the emergency department

Open Access Emergency Medicine, 2017
Charles R Caffrey, Patrick M Lank Department of Emergency Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA Abstract: Patients can use numerous drugs that exist outside of existing regulatory statutes in order to get “
Caffrey CR, Lank PM
doaj  

Unexpected Detection of Psilocybin in a 100 mg Tramadol Tablet: A Forensic Case Report [PDF]

Asia Pacific Journal of Medical Toxicology
Background: Tramadol is a synthetic opioid analgesic prescribed for moderate pain. Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) is a naturally occurring psychoactive compound found in certain mushrooms, often referred to as "magic mushrooms" and ...
Amin Reihani, Fatemeh Shaki
doaj   +1 more source