Results 61 to 70 of about 27,070 (238)

Cognition, emotion, and the alcohol - Aggression relationship:Comment on Giancola (2000) [PDF]

open access: yes, 2000
P. R. Giancola's (2000) thesis that the alcohol-aggression relationship can be explained by alcohol-induced disruption of executive cognitive functions mediated by the prefrontal cortex is critically examined. At moderate doses, alcohol has been reported
Lyvers, M.
core   +1 more source

Changes over time in hallucinogen‐related emergency department visits in Ontario, Canada

open access: yesAddiction, EarlyView.
Abstract Background and aims Recent increasing interest in hallucinogens has underscored the critical gaps in our understanding of their adverse health effects and healthcare usage over time. The current study aimed to examine changes in emergency department (ED) visit rates involving hallucinogens, clinical outcomes of visits and the characteristics ...
Daniel T. Myran   +9 more
wiley   +1 more source

Psychedelic Fauna for Psychonaut Hunters: A Mini-Review

open access: yesFrontiers in Psychiatry, 2018
Currently different classes of psychoactive substances are easily available for abuse, including several hundred novel psychoactive substances (NPS).
Laura Orsolini   +10 more
doaj   +1 more source

The association between sleep disturbance and stimulant use: A cross‐lagged examination

open access: yesAddiction, EarlyView.
Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian   +12 more
wiley   +1 more source

Metates and Hallucinogens in Costa Rica

open access: yesPapers from the Institute of Archaeology, 1991
Metates are grinding stones on which corn and other substances are ground with hand-held stones called manos. A clue that grinding stones were associated with mushroom rituals is, for example, provided by a tripod metate from NW Costa Rica belonging to ...
doaj   +2 more sources

Unexpected Detection of Psilocybin in a 100 mg Tramadol Tablet: A Forensic Case Report [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology
Background: Tramadol is a synthetic opioid analgesic prescribed for moderate pain. Psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) is a naturally occurring psychoactive compound found in certain mushrooms, often referred to as "magic mushrooms" and ...
Amin Reihani, Fatemeh Shaki
doaj   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo   +13 more
wiley   +1 more source

Novel Psychoactive Substances 14Recent Progress on Neuropharmacological Mechanisms of Action for Selected Drugs [PDF]

open access: yes, 2017
A feature of human culture is that we can learn to consume chemical compounds, derived from natural plants or synthetic fabrication, for their psychoactive effects.
Boris B. , Quednow   +8 more
core   +1 more source

A sustainable AQbD-based UHPLC–MS/MS method for the determination of hallucinogenic phenethylamines in urine

open access: yesOpen Chemistry
A systematic Analytical Quality by Design (AQbD) approach was applied to the development and validation of a UHPLC–MS/MS method for the determination of hallucinogenic phenethylamine-derived novel psychoactive substances in urine. Owing to the continuous
Kostić Emilija   +3 more
doaj   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander   +5 more
wiley   +1 more source

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