Results 81 to 90 of about 27,070 (238)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Patterns and transitions in substance use among young Swiss men: a latent transition analysis approach [PDF]

, 2014
This study investigates the potential stages of drug use. Data from the longitudinal Cohort Study on Substance Use Risk Factors were used (N = 5,116). Drug use (alcohol, tobacco, and 16 illicit drugs) over the previous 12 months was assessed at two time ...
Baggio, S., Daeppen, J.-B., Deline, S., Dupuis, M., Gmel, G., Henchoz, Y., Mohler-Kuo, M., N'Goran, A., Studer, J.   +8 more
core   +1 more source

The Non-Peptide Arginine-Vasopressin v1a Selective Receptor Antagonist, SR49059, Blocks the Rewarding, Prosocial, and Anxiolytic Effects of 3,4-Methylenedioxymethamphetamine and Its Derivatives in Zebra Fish

Frontiers in Psychiatry, 2017
3,4-Methylenedioxymethamphetamine (MDMA) and its derivatives, 2,5-dimethoxy-4-bromo-amphetamine hydrobromide (DOB) and para-methoxyamphetamine (PMA), are recreational drugs whose pharmacological effects have recently been attributed to serotonin 5HT2A/C ...
Luisa Ponzoni, Daniela Braida, Gianpietro Bondiolotti, Mariaelvina Sala   +3 more
doaj   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source

Return of the lysergamides. Part IV: Analytical and pharmacological characterization of lysergic acid morpholide (LSM-775) [PDF]

, 2018
Lysergic acid diethylamide (LSD) is perhaps one of the best-known psychoactive substances and many structural modifications of this prototypical lysergamide have been investigated. Several lysergamides were recently encountered as “research chemicals” or
Abramson, Abramson, Araneda, Ashby, Babij, Blair, Brandt, Brandt, Brandt, Brandt, Canal, Chemel, Darmani, Darmani, Darmani, Dilly, Dursun, Forster, Fox, Gasser, Gerber, Gogerty, González-Maeso, Gudelsky, Halberstadt, Halberstadt, Halberstadt, Halberstadt, Halberstadt, Halberstadt, Heal, Hintzen, Hoffman, Hofmann, Isbell, Karst, Kim, Kleven, Kraehenmann, Krebs-Thomson, Li, Marona-Lewicka, Martel, Matsumoto, Nakahara, Newman-Tancredi, Nichols, Nichols, Nichols, Nichols, Pokorny, Preller, Rényi, Salmi, Schreiber, Serafine, Sheldrick, Sheldrick, Silva, Stoll, Strassman, Testa, Valle, Vetulani, Vickers, Vollenweider, Wacker, Watts   +67 more
core   +1 more source

Psylocybin and Psilocin as new tools to fight depression

RevSALUS, 2022
Sofia Lemos Martins, Andreia Machado Brito-da-Costa, Áurea Madureira-Carvalho, Ricardo Jorge Dinis-Oliveira, Diana Dias da Silva   +4 more
doaj   +1 more source

Clinical and Prognostic Findings in Psychotropic Substance Poisoning: A Cross-sectional Study [PDF]

Pharmaceutical and Biomedical Research
Background: Psychotropic substance poisoning is a growing public health concern.  Objectives: This study aimed to investigate patients with psychedelic poisoning and evaluate the frequency of clinical, preclinical, and prognostic findings.
Hanieh Hatampour, Hamid Reza Jamshidi, Komeil Aghazadeh-Habashi, Sareh Rafatmagham, Farhad Farnaghi, Hamidreza Ghasemirad, Mehrnoush Giahi Yazdi, Mohsen Jabari, Khashayar Moravej, Hamid Owliaey   +9 more
doaj  

Holistic approach to substance‐induced psychosis

Addiction, EarlyView.
Julia M. Lappin, Shane Darke, Michael Farrell   +2 more
wiley   +1 more source

Conventional cigarettes, novel heated tobacco products, and self‐reported frequent headache association in Japanese individuals: Insights from the JASTIS study, a Japanese cross‐sectional analysis

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Headache is a common health problem, and tobacco products, such as conventional cigarettes and heated tobacco products (HTPs), may be associated with it. Using data from over 23,000 adults in the Japan Society and New Tobacco Internet Survey, we examined the relationships between cigarette and HTP use and self‐reported frequent ...
Masahito Katsuki, Kieran Moran, Muneto Tatsumoto, Keisuke Suzuki, Tomokazu Shimazu, Yasuhiko Matsumori, Yutaro Fuse, Miguel Á. Huerta, Daijiro Sugiyama, Jackson T. S. Cheung, Siobhán O'Connor, Tomás Ward, Takahiro Tabuchi   +12 more
wiley   +1 more source

The Irony of Liberation in One Flew Over the Cuckoo's Nest

The Journal of American Culture, EarlyView.
ABSTRACT The 1975 film One Flew Over the Cuckoo's Nest vividly portrays the tragic consequences of repressive psychiatric authority. The film was—and remains—one of the most memorable and well‐known products of anti‐psychiatry sentiment. Opponents of American psychiatry from the time period of Cuckoo's Nest objected to what they saw as social control ...
Laura Hirshbein
wiley   +1 more source