Results 81 to 90 of about 313 (213)

Efficient and Accurate Force Replay in Cosmological-baryonic Simulations

The Astrophysical Journal
We construct time-evolving gravitational potential models for a Milky Way–mass galaxy from the FIRE-2 suite of cosmological-baryonic simulations using basis function expansions.
Arpit Arora, Robyn Sanderson, Christopher Regan, Nicolás Garavito-Camargo, Emily Bregou, Nondh Panithanpaisal, Andrew Wetzel, Emily C. Cunningham, Sarah R. Loebman, Adriana Dropulic, Nora Shipp   +10 more
doaj   +1 more source

Exploring the Design Space of Low-Thrust Transfers with Ballistic Terminal Coast Segments in Cis-Lunar Space

Aerospace
Spacecraft catering to the Lunar Gateway or other “permanent” stations in the lunar vicinity would require frequent travel between periodic orbits around the Earth–Moon L1 and L2 Lagrange points.
Kevin I. Alvarado, Sandeep K. Singh
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Black hole surrounded by the pseudo-isothermal dark matter halo

European Physical Journal C: Particles and Fields
In this paper, we obtain a new spherically symmetric black hole surrounded by the pseudo-isothermal dark matter halo. Furthermore, to explore the effects of the pseudo-isothermal halo profile on a rotating black hole at the M87 galactic center, we derive
Yi Yang, Dong Liu, Ali Övgün, Gaetano Lambiase, Zheng-Wen Long   +4 more
doaj   +1 more source

Comparison Study of Earth Observation Characteristics between Moon-Based Platform and L1 Point of Earth-Moon System

Remote Sensing
The unceasing quest for a profound comprehension of the Earth system propels the continuous evolution of novel methods for Earth observation. Of these, the Lagrange points situated in the cislunar space proffer noteworthy prospects for space-based Earth ...
Runbo Dong, Huadong Guo, Guang Liu
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

The capture of halo material by orbiting subhaloes

8 pages, 9 figures.
Yang, Hang, White, Simon D. M., Gao, Liang   +2 more
openaire   +2 more sources

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

New analytical model of static black hole with a dark matter halo and parametric constraints through quasiperiodic oscillations

European Physical Journal C: Particles and Fields
A novel analytical Schwarzschild-like black hole (BH) solution is derived. It exhibits a static BH with a dark matter (DM) halo characterized by a Dehnen-type density profile. This solution could represent an alternative perspective on the interaction of
Uktamjon Uktamov, Sanjar Shaymatov, Bobomurat Ahmedov, Chengxun Yuan   +3 more
doaj   +1 more source