Results 61 to 70 of about 5,644 (180)

Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead

open access: yesAdvanced Genetics, Volume 6, Issue 3, September 2025.
Optogenetics provides up to millisecond scale, cell type‐specific control of biology using light‐sensitive proteins. This review chronicles two decades of tool development, from microbial rhodopsins and photoactivated enzymes to allosteric switches, surveys broad applications in neuroscience, molecular and cell biology, cardiology, immunology, and ...
Xiao Duan, Mo Zhu, Shiqiang Gao
wiley   +1 more source

Structure analysis of biologically important prokaryotic glycopolymers [PDF]

open access: yes, 2013
Of the many post-translational modifications organisms can undertake, glycosylation is the most prevalent and the most diverse. The research in this thesis focuses on the structural characterisation of glycosylation in two classes of glycopolymer (
Ventura, Valeria Victoria   +1 more
core   +1 more source

A Spotlight on Archaea in Humans, Livestock and Poultry: A Review

open access: yesVeterinary Medicine and Science, Volume 11, Issue 2, March 2025.
The microbiota includes prokaryotes (archaea and bacteria) and eukaryotes. Archaea are single‐celled prokaryotes and essential part of gut microbiome. Researches on archaea in ruminants and humans are more than mono‐gastric. The low abundance of archaea in the gut depends on the method used (metagenomics or meta‐transcriptomic) and age of people or ...
Ahmad Salahi, Wafaa A. Abd El‐Ghany
wiley   +1 more source

Chromatin and gene regulation in archaea

open access: yesMolecular Microbiology, Volume 123, Issue 3, Page 218-231, March 2025.
Recent data from diverse archaea with different repertoires of nucleoid‐associated proteins show a common genome‐wide chromatin organisation where chromatin maintains access to gene promoters independently of transcription activity. Abstract The chromatinisation of DNA by nucleoid‐associated proteins (NAPs) in archaea ‘formats’ the genome structure in ...
Fabian Blombach, Finn Werner
wiley   +1 more source

Identification of a system required for the functional surface localization of sugar binding proteins with class III signal peptides in Sulfolobus solfataricus [PDF]

open access: yes, 2007
The hyperthermophilic archaeon Sulfolobus solfataricus contains an unusual large number of sugar binding proteins that are synthesized as precursors with a class III signal peptide.
Albers S.V.   +12 more
core   +4 more sources

Archaeal Signalling Networks—New Insights Into the Structure and Function of Histidine Kinases and Response Regulators of the Methanogenic Archaeon Methanosarcina acetivorans

open access: yesEnvironmental Microbiology, Volume 27, Issue 2, February 2025.
Methanosarcina acetivorans possesses extensive signal transduction systems, including 53 histidine kinases and 15, mainly REC‐only, response regulators. All recombinant versions of representative kinase types except MA_type 2 showed autokinase activity.
Nora F. K. Georgiev   +4 more
wiley   +1 more source

Identification of the arginine/ornithine antiporter ArcD from Halobacterium salinarum [PDF]

open access: yesFEBS Letters, 2008
This paper identifies the first arginine/ornithine antiporter ArcD from the domain of archea. The functional role of ArcD is demonstrated by transport assays with radioactive labelled arginine, by its necessity to enable arginine fermentation under anaerobic growth conditions and by the consumption of arginine from the medium during growth.
Wimmer, F.   +4 more
openaire   +3 more sources

Channelrhodopsin‐2 Oligomerization in Cell Membrane Revealed by Photo‐Activated Localization Microscopy

open access: yesAngewandte Chemie, Volume 136, Issue 11, March 11, 2024.
Insights from super‐resolution microscopy: Channelrhodopsin‐2 (ChR2), a widely used optogenetic tool, forms dimers, not higher oligomers, in human cell membranes. Disruption of inter‐protein disulfide bonds leads to partial ChR2 monomerization, particularly in cells with lower ChR2 densities.
Ekaterina Bestsennaia   +13 more
wiley   +2 more sources

The separation between mRNA‐ends is more variable than expected

open access: yesFEBS Open Bio, Volume 14, Issue 12, Page 1985-1995, December 2024.
Both mRNA ends are in proximity despite mRNAs origin, length and secondary or tertiary structures. However, we show that the distance between native mRNA ends is not constant and varies across organisms. We found that native sequences show much larger variations than those observed in random sequences, implying the existence of a biological mechanism ...
Nancy Gerling   +3 more
wiley   +1 more source

Synthesis retinal analogues of spiropyran derivaties, investigation they interactions with bacteriorhodopsin from H. salinarum

open access: yesТонкие химические технологии, 2006
The opportunity of design of analogue retinal with replacement of trimethylhexenic ring of a molecule on spiropyran moiety is shown. Process of interaction of the synthesized retinal analogues with bacterioopsin from apomembrane Halobacterium salinarum ...
A. V. Laptev   +2 more
doaj  

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