Results 1 to 10 of about 61,813 (248)

Co‐Expression of Tardive Dyskinesia and Drug‐Induced Parkinsonism in Rats Chronically Treated With Haloperidol [PDF]

Neuropsychopharmacology Reports
Aim We aimed to create a rat model of drug‐induced parkinsonism and tardive dyskinesia by chronic administration of haloperidol and examine the expression of direct and indirect pathway markers in the striatum of the model rats.
Iku Kinoshita, Haruo Nishijima, Takashi Nakamura, Tomoya Kon, Shuji Shimoyama, Hiroki Hikichi, Chieko Suzuki, Masahiko Tomiyama   +7 more
doaj   +2 more sources

Haloperidol for Pain Management: A Narrative Review [PDF]

Pharmaceuticals
The use of haloperidol in pain management has been a topic of interest for several decades. Haloperidol is a widely used antipsychotic medication with unique pharmacologic properties that make it a potential candidate for pain management.
Carlos J. Roldan, Jonathan W. Rowland, Alice L. Ye   +2 more
doaj   +2 more sources

Haloperidol for the Treatment of Delirium in ICU Patients

New England Journal of Medicine, 2022
METHODS In this multicenter, blinded, placebo-controlled trial, we randomly assigned adult patients with delirium who had been admitted to the ICU for an acute condition to receive intravenous haloperidol (2.5 mg 3 times daily plus 2.5 mg as needed up to
N. Andersen-Ranberg, Lone M. Poulsen, A. Perner, J. Wetterslev, S. Estrup, J. Hästbacka, Matthew Morgan, G. Citerio, J. Caballero, T. Lange, M. N. Kjær, B. Ebdrup, Janus Engstrøm, M. H. Olsen, Marie Oxenbøll Collet, C. Mortensen, Sven-Olaf Weber, A. S. Andreasen, M. Bestle, B. Uslu, Helle Scharling Pedersen, Louise Gramstrup Nielsen, Hans C Toft Boesen, Jacob V Jensen, Lars Nebrich, Kirstine N la Cour, J. Laigaard, Cecilie Haurum, Marie W Olesen, C. Overgaard-Steensen, B. Westergaard, B. Brand, Gitte Kingo Vesterlund, Pernille Thornberg Kyhnauv, V. S. Mikkelsen, S. Hyttel-Sorensen, I. de Haas, S. Aagaard, L. O. Nielsen, A. S. Eriksen, B. Rasmussen, Helene Brix, T. Hildebrandt, Martin Schønemann-Lund, H. Fjeldsøe-Nielsen, Anna-Maria Kuivalainen, O. Mathiesen   +46 more
semanticscholar   +1 more source

Incidence of Orthostatic Hypotension in Schizophrenic Patients Using Antipsychotics at Sambang Lihum Mental Health Hospital, South Kalimantan

Borneo Journal of Pharmacy, 2021
Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya, Sandra Putri Wijaya, Khoerul Anwar   +2 more
doaj   +1 more source

Differential changes in QTc duration during in-hospital haloperidol use. [PDF]

PLoS ONE, 2011
AIMS: To evaluate changes in QT duration during low-dose haloperidol use, and determine associations between clinical variables and potentially dangerous QT prolongation. METHODS: In a retrospective cohort study in a tertiary university teaching hospital
Marieke T Blom, Abdennasser Bardai, Barbara C van Munster, Mei-Ing Nieuwland, Hendrik de Jong, Daniel A van Hoeijen, Anne M Spanjaart, Anthonius de Boer, Sophia E de Rooij, Hanno L Tan   +9 more
doaj   +1 more source

Acute Extrapyramidal Side Effects from Smoked Haloperidol

Case Reports in Psychiatry, 2021
Introduction. Haloperidol is a dopamine receptor antagonist used to treat patients with psychotic disorders. Especially at high doses, haloperidol carries a higher risk of extrapyramidal symptoms (EPS) compared to second-generation antipsychotics.
Angeline Pham, Joo-Young Lee, Christopher W. T. Miller   +2 more
doaj   +1 more source

Effects of cannabidiol on weight and fasting blood sugar with chronic and subchronic haloperidol administration

Discover Mental Health, 2022
Objectives The duration of administration (e.g., subchronic or chronic) of haloperidol may influence its adverse effects. We studied the effects of duration of administration of haloperidol on body weight and fasting blood sugar (FBS).
Jaiyeola Abiola Kajero, Soraya Seedat, Jude U. Ohaeri, Abidemi Akindele, Oluwagbemiga Aina   +4 more
doaj   +1 more source

Observational study of haloperidol in hospitalized patients with COVID-19

medRxiv, 2020
Background: Haloperidol, a widely used antipsychotic, has been suggested as potential effective treatment for Covid-19 on the grounds of its in-vitro antiviral effects against SARS-CoV-2.
N. Hoertel, Marina Sánchez Rico, R. Vernet, A. Jannot, A. Neuraz, C. Blanco, C. Lemogne, G. Airagnes, N. Paris, C. Daniel, Alexandre Gramfort, G. Lemaître, M. Bernaux, A. Bellamine, N. Beeker, F. Limosin   +15 more
semanticscholar   +1 more source

Assessment of Protective Effects of Carvacrol on Haloperidol-Induced Oxidative Stress and Genotoxicity in Human Peripheral Blood Lymphocytes

Journal of Toxicology, 2022
Haloperidol is a first-generation antipsychotic drug that has several indications in a wide range of mental conditions. The extensive prescription of haloperidol is correlated with some less-known adverse effects such as genotoxicity.
Ehsan Zamani, Alireza Ahmadi Shad, Hediye Fatemi, Saba Mahboubi, Azadeh Motavallian, Mehdi Evazalipour   +5 more
doaj   +1 more source

Insights into the biased activity of dextromethorphan and haloperidol towards SARS-CoV-2 NSP6: in silico binding mechanistic analysis

Journal of molecular medicine, 2020
The outbreak of novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus continually led to infect a large population worldwide.
P. Pandey, Kartikay Prasad, Amresh Prakash, Vijay Kumar   +3 more
semanticscholar   +1 more source