Rapid tranquilization for agitated patients in emergency psychiatric rooms: a randomized trial of olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone Tranquilização rápida para pacientes agitados nos serviços de emergência psiquiátrica: um ensaio clínico randomisado de olanzapina, ziprasidona, haloperidol mais prometazina, haloperidol mais midazolam e haloperidol em monoterapia [PDF]
Brazilian Journal of Psychiatry, 2011 OBJECTIVE: To compare the effectiveness of intramuscular olanzapine, ziprasidone, haloperidol plus promethazine, haloperidol plus midazolam and haloperidol alone as the first medication(s) used to treat patients with agitation and aggressive behavior ...
Leonardo Baldaçara +3 more
doaj +5 more sources
Effects of Haloperidol on Cardiac Histamine H2 Receptors and β-Adrenoceptors in Isolated Mouse and Human Atrial Preparations [PDF]
NeuroSciThe antipsychotic drug haloperidol is found on the WHO list of essential drugs. In vitro, haloperidol demonstrates binding affinity for various receptors, including histamine H2 receptors (H2Rs).
Jonas M. A. Schlicht +4 more
doaj +2 more sources
Chronic haloperidol exposure impairs neurodevelopment via Notch1 signaling in human stem cell-derived brain organoids [PDF]
Scientific ReportsHaloperidol is a typical antipsychotic used to treat schizophrenia and induces dopamine D2 receptor antagonism. Long-term use of haloperidol can reduce brain size in animals and humans; however, the underlying mechanism of this effect remains unclear ...
Hyunsu Kang +3 more
doaj +2 more sources
Borneo Journal of Pharmacy, 2021 Schizophrenia is a psychiatric disorder that requires antipsychotics therapy. Antipsychotics cause many side effects, including orthostatic hypotension.
Noor Cahaya +2 more
doaj +1 more source
Differential changes in QTc duration during in-hospital haloperidol use. [PDF]
PLoS ONE, 2011 AIMS: To evaluate changes in QT duration during low-dose haloperidol use, and determine associations between clinical variables and potentially dangerous QT prolongation. METHODS: In a retrospective cohort study in a tertiary university teaching hospital
Marieke T Blom +9 more
doaj +1 more source
Discover Mental Health, 2022 Objectives The duration of administration (e.g., subchronic or chronic) of haloperidol may influence its adverse effects. We studied the effects of duration of administration of haloperidol on body weight and fasting blood sugar (FBS).
Jaiyeola Abiola Kajero +4 more
doaj +1 more source
Acute Extrapyramidal Side Effects from Smoked Haloperidol
Case Reports in Psychiatry, 2021 Introduction. Haloperidol is a dopamine receptor antagonist used to treat patients with psychotic disorders. Especially at high doses, haloperidol carries a higher risk of extrapyramidal symptoms (EPS) compared to second-generation antipsychotics.
Angeline Pham +2 more
doaj +1 more source
Antipsychotic medication for childhood-onset schizophrenia [PDF]
, 2007 We review the development of several new approaches for extending the performance of Brillouin based slow light systems. In particular we describe the use of cavity effects to enhance the achievable delays, gain saturation to decouple the delay and ...
Datta, Soumitra +2 more
core +3 more sources
Journal of Toxicology, 2022 Haloperidol is a first-generation antipsychotic drug that has several indications in a wide range of mental conditions. The extensive prescription of haloperidol is correlated with some less-known adverse effects such as genotoxicity.
Ehsan Zamani +5 more
doaj +1 more source
No association of a set of candidate genes on haloperidol side effects. [PDF]
, 2012 We previously investigated a sample of patients during an active phase of psychosis in the search for genetic predictors of haloperidol induced side effects.
De Ronchi, Diana +8 more
core +4 more sources