Results 31 to 40 of about 75,245 (304)

Caffeine and Halothane Sensitivity of Intracellular Ca2+ Release Is Altered by 15 Calcium Release Channel (Ryanodine Receptor) Mutations Associated with Malignant Hyperthermia and/or Central Core Disease*

open access: yesJournal of Biological Chemistry, 1997
Malignant hyperthermia (MH) and central core disease (CCD) are autosomal dominant disorders of skeletal muscle in which a potentially fatal hypermetabolic crisis can be triggered by commonly used anesthetic agents.
Jiefei Tong   +5 more
semanticscholar   +1 more source

Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]

open access: yes, 2019
Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A.   +5 more
core   +1 more source

Diagnosis of drug induced liver injury using a lymphocyte blast transformation test based on whole blood culture [PDF]

open access: yes, 1977
Twenty cases of suspected drug induced liver injury (16 cases of which satisfied the criteria for at least a query positive diagnosis as based on the Fourth Congress of "Drugs and the Liver" in Japan) were studied by the whole blood culture ...
Takata, Shinji
core   +1 more source

Carcass quality of crossbred pigs with Pietrain as a terminal sire

open access: yesItalian Journal of Animal Science, 2010
The aim of this paper was to investigate the effect of the crossbreed and halothane genotype on carcass quality traits of fatteners from commercial pig farm.
Zoran Luković   +2 more
doaj   +1 more source

Halothane modulation of skeletal muscle ryanodine receptors: dependence on Ca2+, Mg2+, and ATP.

open access: yesAmerican Journal of Physiology - Cell Physiology, 2008
Malignant hyperthermia (MH) susceptibility is a genetic disorder of skeletal muscle associated with mutations in the ryanodine receptor isoform 1 (RyR1) of sarcoplasmic reticulum (SR).
P. Diaz-Sylvester   +2 more
semanticscholar   +1 more source

Sensitivity of inhalation anesthetics isoflurane and sevoflurane for the drug-induced QT-interval prolongation in guinea pigs

open access: yesJournal of Pharmacological Sciences, 2020
We investigated effects of isoflurane and sevoflurane on sparfloxacin-induced QT-interval prolongation in guinea pigs under the monitoring of electrocardiogram and monophasic action potential (MAP), which was compared with those of halothane or non ...
Yoshinobu Nagasawa   +5 more
doaj  

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

open access: yes, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L   +5 more
core   +1 more source

Kinetics of desflurane, isoflurane, and halothane in humans.

open access: yesAnesthesiology, 1991
The low solubility of desflurane in blood and tissues suggests that the partial pressures of this agent in blood and tissues should approach the inspired partial pressure more rapidly than would the blood and tissue partial pressures of other potent ...
N. Yasuda   +6 more
semanticscholar   +1 more source

Glial Versus Neuronal Na+/K+‐ATPase in Activity‐Evoked K+ Clearance and Their Sensitivity to Elevated Extracellular K+

open access: yesGlia, EarlyView.
The glial Na+ pump regulates [K+]o during neuronal activity, and the neuronal version restores [K+]o to baseline. Spreading depression‐related rise of K+ does not cause SD propagation via suppression of Na+/K+‐ATPase or glutamate transport. ABSTRACT Neuronal activity in the central nervous system is associated with a [K+]o transient that is swiftly ...
Brian Skriver Nielsen   +6 more
wiley   +1 more source

A Comparative Study of Cell Specific Effects of Systemic and Volatile Anesthetics on Identified Motor Neurons and Interneurons of Lymnaea stagnalis (L.), Both in the Isolated Brain and in Single Cell Culture

open access: yesFrontiers in Physiology, 2019
1. A comparative descriptive analysis of systemic (sodium pentobarbital, sodium thiopentone, ketamine) and volatile (halothane, isoflurane, enflurane) general anesthetics revealed important differences in the neuronal responses of identified motor ...
Hadi Fathi Moghadam   +6 more
doaj   +1 more source

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