Results 41 to 50 of about 53,008 (253)

Calcium Homeostasis in Myogenic Differentiation Factor 1 (MyoD)-Transformed, Virally-Transduced, Skin-Derived Equine Myotubes [PDF]

open access: yes, 2014
Dysfunctional skeletal muscle calcium homeostasis plays a central role in the pathophysiology of several human and animal skeletal muscle disorders, in particular, genetic disorders associated with ryanodine receptor 1 (RYR1) mutations, such as malignant
A Hovnanian   +75 more
core   +5 more sources

Real‐World Impact on Postoperative Vomiting by Changing Anesthesia Regimens in Children Undergoing Strabismus Surgery: An Interrupted Time Series Analysis

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Preventive measures for postoperative vomiting (POV) in pediatric strabismus surgery are essential. Previous experimental studies have shown the independent antiemetic effects of propofol‐based total intravenous anesthesia (TIVA), dexamethasone (DEX), and ondansetron (OND).
Taiki Kojima   +5 more
wiley   +1 more source

Enantioconvergent Cobalt‐Catalyzed Hydroalkylation for the Construction of Fluoro, Chloro, and Trifluoromethyl Stereogenic Centers

open access: yesAngewandte Chemie, Volume 137, Issue 32, August 4, 2025.
Cobalt‐hydride catalyzed enantioconvergent hydroalkylation with allenes and alkenes is achieved with high chemo‐, regio‐, and enantioselectivity. This method allows the streamlined synthesis of enantiomerically enriched C(sp3)–fluorine, –chlorine, and –trifluoromethyl stereocenters.
Uttam Dhawa, Xile Hu
wiley   +2 more sources

HALOTHANE AND THE HEART

open access: yesBritish Journal of Anaesthesia, 1968
SUMMARY The cardiac output fall and the rate changes observed with halothane-oxygen anaesthesia represent a homeostatic adjustment to greater oxygen extraction per unit volume of blood, secondary to 98 per cent oxygen breathing and to a decreased oxygen demand of the anaesthetized patient.
John E. Mazuzan   +2 more
openaire   +3 more sources

Cardiac arrest in a child during a combined general epidural anesthesia procedure [PDF]

open access: yes, 2005
An increased risk of perioperative cardiac arrest in children, in comparison to adults, has been recognized. A number of factors associated with perioperative cardiac arrest have been identified, including young age, comorbidities, and emergency ...
Prabakti, Yudhi   +4 more
core  

Elevated cortisol concentration in preterm sheep fetuses impacts heart development

open access: yesExperimental Physiology, EarlyView.
Abstract The prepartum rise in cortisol promotes cardiac development and maturation. Here, we investigated the impact of elevated circulating cortisol during mid‐late gestation on cardiac growth and metabolism in fetal sheep. Saline or cortisol (2–3 mg in 4.4 mL/24 h) was infused into the fetal jugular vein from 109 to 116 days gestation (dG, term ...
Reza Amanollahi   +9 more
wiley   +1 more source

Halothane Increases Myocardial Sensitivity to Epinephrine-Induced Arrhythmias in Cirrhotic Rats

open access: yesArchives of Anesthesia and Critical Care, 2016
Background: Cirrhotic patients are at a greater risk of different kinds of arrhythmias. Despite the well-known arrhythmogenic effects of halothane, developing countries continue to use halothane due to its low cost. This study was designed to investigate
Mahmoud Gorji valokola   +8 more
doaj  

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

Global anaesthesia practice using inguinal hernia surgery as a tracer condition: a secondary analysis of an international prospective cohort study

open access: yesAnaesthesia, Volume 80, Issue 11, Page 1343-1351, November 2025.
Summary Introduction Restoration of surgical capacity is essential to post‐COVID‐19 recovery. This study explored the use and safety of anaesthesia options for inguinal hernia surgery, a common tracer condition, to describe current global practice and highlight opportunities to build the capacity of health systems.
NIHR Global Health Research Group on Environmentally Sustainable Hospitals in Low‐ and Middle‐income Countries   +5007 more
wiley   +1 more source

Qualitative and Quantitative Characteristics of the Electroencephalogram in Normal Horses during Administration of Inhaled Anesthesia. [PDF]

open access: yes, 2015
BackgroundThe effects of anesthesia on the equine electroencephalogram (EEG) after administration of various drugs for sedation, induction, and maintenance are known, but not that the effect of inhaled anesthetics alone for EEG recording.ObjectiveTo ...
Aleman, M   +8 more
core   +1 more source

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