Results 161 to 170 of about 37,629 (254)

Sensing‐Integrated Patient‐Derived Tumorspheres Predict Chemotherapeutic Efficacy via Local Extracellular pH Dynamics

Small, EarlyView.
The study introduces a 3D sensing‐integrated platform enabling real‐time, non‐invasive monitoring of pH dynamics in patient‐derived PDAC tumorspheres. It revealed distinct extracellular acidification patterns under FOLFIRINOX, gemcitabine, and paclitaxel, correlating with therapeutic efficacy.
Stefania Forciniti, Valentina Onesto, Anna Chiara Siciliano, Helena Iuele, Stefano D'Ugo, Norma Depalma, Cinzia Fasano, Alessandro D'Amuri, Giuseppe Gigli, Marcello G. Spampinato, Loretta L. del Mercato   +10 more
wiley   +1 more source

Influence of High-Genetic-Potential Lineages and Sex on Carcass Traits and Pork Quality. [PDF]

Animals (Basel)
Cavalcanti ÉNF, Dutra DR, Villegas-Cayllahua EA, Fidelis HA, Giampietro-Ganeco A, Pereira MR, Ferrari FB, Rodrigues RA, Belo MAA, Borba H.   +9 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Human amniotic membrane as an extracellular matrix scaffold in regenerative endodontics: A cell homing perspective. [PDF]

J Conserv Dent Endod
Ferrao TMC, Ataide IN, Lambor R.
europepmc   +1 more source

Transposons as Tools for Future Genome Engineering in Yeasts and Filamentous Fungi

Yeast, EarlyView.
Applications of transposon‐based tools for genome engineering in fungi include transposon‐mediated mutagenesis and targeted genomic integration. ABSTRACT Transposons are fundamental genetic elements that have profoundly shaped the architecture of eukaryotic genomes.
Bingyin Peng, Masahiro Tominaga, Chengqiang Wang, Robert E. Speight, Jun Ishii   +4 more
wiley   +1 more source

Effects of 222 nm Far-UVC Light on Color and Lipid Oxidation in Ready-to-Eat Deli Ham and Turkey During Storage. [PDF]

Foods
McDonald JJ, Wang YC, Harsh BN.
europepmc   +1 more source

Dietary and Ranging Behavior of Semi‐Free Ranging Lemur catta and Varecia rubra at Myakka City Lemur Reserve, Florida, USA

Zoo Biology, EarlyView.
Betsiboka, a female red ruffed lemur (Varecia rubra) eating Carolina redroot in the Tower forest. ABSTRACT Lemurs are severely threatened due to anthropogenic habitat loss and climate change. Therefore, understanding how lemurs adapt their diets to novel habitats is critically important for maintaining healthy wild populations and effectively managing ...
Ethan Gulledge, Hannah L. Lyles, Lydia E. O. Light, Taylor Fisher, Elizabeth Gandy, Bruce Holst, Timothy D. Bransford, Erik R. Patel   +7 more
wiley   +1 more source

Integrated in vitro and multi-cohort cross-omics analysis of HTLV-1-associated lung pathology reveals a RelA-dependent mechanism for monocyte recruitment and differentiation. [PDF]

Mol Med
Heymann CJF, Gouwy M, Hermans R, Twizere JC, Assone T, Casseb J, Racine I, Cleynen I, Murphy EL, Bruhn R, Schols D, Vanderlinden E, Van Weyenbergh J.   +12 more
europepmc   +1 more source

No gain from pain: Lack of nociceptor activation suggests no adaptation for defence in the evolution of European viper venoms

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Snake venoms show variability in composition at all taxonomic levels, both within and between species, and the selective pressures underlying this variation have long been debated.
Bálint Üveges, Samuel D. Robinson, Vanessa Schendel, Edvárd Mizsei, Ana Ćuriċ, Maria Dimaki, Vincenzo Ferri, Silviu Petrovan, Andrea V. Pozzi, Tihomir Radonjiċ, Tibor Sos, Jeffrey W. Streicher, Alexandru Strugariu, Emina Šunje, Ștefan Zamfirescu, Oleksandr Zinenko, Irina Vetter, Wolfgang Wüster   +17 more
wiley   +1 more source

Downregulation of the deubiquitinating enzyme USP10 correlates with neuronal apoptosis in HTLV-1-associated myelopathy. [PDF]

Sci Rep
Arishima S, Takahashi M, Dozono M, Yoshida T, Nozuma S, Takashima H, Fujii M, Kubota R.   +7 more
europepmc   +1 more source