Results 101 to 110 of about 19,908 (281)
Rolling-circle replication of viroids, viroid-like satellite RNAs and hepatitis delta virus: variations on a theme [PDF]
, 1999 Viroids and viroid-like satellite RNAs from plants, and the human hepatitis delta virus (HDV) RNA share some properties that include small size, circularity and replication through a rolling-circle mechanism.
Flores, Ricardo +5 more
core +1 more source
Journal of Chemical Theory and Computation, 2011 We report results from combined quantum mechanical/molecular mechanical (QM/MM) free energy simulations to explore metal-assisted phosphoryl transfer and general acid catalysis in the extended hammerhead ribozyme.
K. Wong, Tai-Sung Lee, D. York
semanticscholar +1 more source
A split ribozyme system for in vivo plant RNA imaging and genetic engineering
Plant Biotechnology Journal, Volume 23, Issue 5, Page 1640-1649, May 2025.Summary RNA plays a central role in plants, governing various cellular and physiological processes. Monitoring its dynamic abundance provides a discerning understanding of molecular mechanisms underlying plant responses to internal (developmental) and external (environmental) stimuli, paving the way for advances in plant biotechnology to engineer crops
Yang Liu +11 more
wiley +1 more source
Biophysica, 2022 The catalytic mechanism of hammerhead ribozymes (HHRzs) attracted great attention in relation to the chemical origin of life. However, the basicity (pKa) of the catalytic sites of HHRzs has not been studied so far.
Yoshiyuki Tanaka +8 more
doaj +1 more source
A high-throughput, quantitative cell-based screen for efficient tailoring of RNA device activity [PDF]
, 2012 Recent advances have demonstrated the use of RNA-based control devices to program sophisticated cellular functions; however, the efficiency with which these devices can be quantitatively tailored has limited their broader implementation in cellular ...
Chang, Andrew L. +3 more
core +4 more sources
Physiologia Plantarum, Volume 177, Issue 2, March/April 2025.Abstract Viral infections are major contributors to crop yield loss and represent a significant threat to sustainable agriculture. Plants respond to virus attacks by activating sophisticated signalling cascades that initiate multiple defence mechanisms.
Kritika Shukla +4 more
wiley +1 more source
Genetic control of mammalian T-cell proliferation with synthetic RNA regulatory systems [PDF]
, 2010 RNA molecules perform diverse regulatory functions in natural biological systems, and numerous synthetic RNA-based control devices that integrate sensing and gene-regulatory functions have been demonstrated, predominantly in bacteria and yeast.
Beisel +27 more
core +3 more sources
Ubiquitous presence of the hammerhead ribozyme motif along the tree of life.
RNA: A publication of the RNA Society, 2010 Examples of small self-cleaving RNAs embedded in noncoding regions already have been found to be involved in the control of gene expression, although their origin remains uncertain.
M. de la Peña, I. García‐Robles
semanticscholar +1 more source
Site‐Selective Modification and Labeling of Native RNA
Chemistry – A European Journal, Volume 31, Issue 12, February 25, 2025.The review highlights recent advancements in site‐selective modification and labeling of native RNA, an important area for the development of RNA therapeutics and fundamental RNA research. The applications, current challenges of existing methods and potential future direction of this field are also discussed.
Tuan‐Khoa Kha, Yiran Zhao, Ru‐Yi Zhu
wiley +1 more source
Discovery of replicating circular RNAs by RNA-seq and computational algorithms. [PDF]
PLoS Pathogens, 2014 Replicating circular RNAs are independent plant pathogens known as viroids, or act to modulate the pathogenesis of plant and animal viruses as their satellite RNAs.
Zhixiang Zhang +13 more
doaj +1 more source