Explanation by a putative triester‐like mechanism for the thio effects and Mn2+ rescues in reactions catalyzed by a hammerhead ribozyme [PDF]
, 1998 Demin Zhou +3 more
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Representation, searching and discovery of patterns of bases in complex RNA structures [PDF]
We describe a graph theoretic method designed to perform efficient searches for substructural patterns in nucleic acid structural coordinate databases using a simplified vectorial representation.
Artymiuk, P.J. +3 more
core +1 more source
Fast and simple purification of chemically modified hammerhead ribozymes using a lipophilic capture tag [PDF]
, 1999 Brian S. Sproat +4 more
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Mini-ribozymes and freezing environment: a new scenario for the early RNA world
, 2005 International audienceThe RNA World hypothesis states that the present-day life, which is based on DNA genomes and protein enzymes, was preceded by a simpler life form based primarily on RNA.
Vlassov, A. V.
core +1 more source
Chemical Modification of Hammerhead Ribozymes [PDF]
, 1995 Leonid Beigelman +15 more
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A fast, efficient and sequence-independent method for flexible multiple segmental isotope labeling of RNA using ribozyme and RNase H cleavage [PDF]
, 2017 Structural information on RNA, emerging more and more as a major regulator in gene expression, dramatically lags behind compared with information on proteins.
Allain, Frédéric H.-T +3 more
core
The Structural Basis of Hammerhead Ribozyme Self-Cleavage [PDF]
, 1998 James B. Murray +6 more
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Evidence for a hydroxide ion bridging two magnesium ions at the active site of the hammerhead ribozyme [PDF]
, 1997 Thomas Hermann
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Aptamers in oncology: a diagnostic perspective [PDF]
, 2008 Nucleic acid sequences can produce a wide variety of three-dimensional conformations. Some of these structural forms are able to interact with proteins and small molecules with high affinity and specificity.
Khan, Huma, Missailidis, Sotiris
core
A 451-nucleotide circular RNA from cherry with hammerhead ribozymes in its strands of both polarities [PDF]
, 1997 Francesco Di Serio +3 more
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