Results 181 to 190 of about 399,690 (387)

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

THE POSSIBLE ROLE OF THE ADRENAL CORTEX IN FLUID SHIFTS IN THE HAMSTER FOLLOWING RENAL DAMAGE [PDF]

, 1952
Frederic J. Agate
openalex   +1 more source

Critical Evaluation of Methods for the Identification of Aneugens

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The genotoxic potential of chemicals must be evaluated in regulatory safety assessment settings, including but not limited to, the development of new pharmaceuticals, industrial chemicals, food and cosmetic ingredients, and agrochemicals. Initial assessment of the chromosome‐damaging potential of chemicals is often conducted in mammalian cells
Xiaowen Sun, Stephen D. Dertinger, Azeddine Elhajouji, Daniel J. Roberts, Jan van Benthem, Maik Schuler, Shambhu Roy, Alexandra Taraboletti, Connie L. Chen   +8 more
wiley   +1 more source

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

Exploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye, Wenhua Huang, Shujuan Yu, Yan Guo, Peng Sun, Ziyuan Chen, Linhui Hao, Yan Zhang, Caixia Li, Yongqiang Jiang, Jun Wu, Li Zhu, Hengliang Wang, Chao Pan   +13 more
wiley   +1 more source

Active transport of amino acids by sacs of everted small intestine of the golden hamster (Mesocricetus auratus)

, 1956
G. Wiseman
openalex   +2 more sources

Neurotoxic Symptoms Produced in the Syrian Hamster (Cricetus Auratus) by Diphtherial Toxin [PDF]

, 1948
L. Olitzki, L. A. Stuczynski, N. Grossowicz   +2 more
openalex   +1 more source

Concentration of radio‐iodide and ³⁵S‐labelled thiocyanate by the stomach of the hamster

, 1956
John Logothetopoulos, N. B. Myant
openalex   +2 more sources

THE SUSCEPTIBILITY OF HAMSTERS TO ERYSIPELOTHRIX RHUSIOPATHIAE [PDF]

, 1950
R. D. Shuman, A. M. Lee
openalex   +1 more source

Do Gadolinium‐Based Contrasts Represent a High Risk for Genotoxicity in Mammalian Cells? A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT The scientific rationale for this review stems from the increasing global use of gadolinium‐based contrast agents in medical imaging and the concerns over the long‐term environmental accumulation of gadolinium waste, which may pose biological risks.
Thiago Guedes Pinto, Rogerio Aparecido Dedivits, Daniel Araki Ribeiro   +2 more
wiley   +1 more source

Probing polarization response of monolayer cell cultures with entangled photon pairs

Journal of Biophotonics, EarlyView.
Innovative optical detection using polarization and quantum techniques is presented for biological sample analysis. This method utilizes non‐classical light, specifically entangled photon pairs, for enhanced sensitivity in low‐photon‐flux environments.
L. Zhang, V. R. Besaga, P. Rühl, C. Zou, S. H. Heinemann, Y. Wang, F. Setzpfandt   +6 more
wiley   +1 more source