Results 61 to 70 of about 17,128,221 (391)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

G protein‐coupled receptors: walking hand‐in‐hand, talking hand‐in‐hand? [PDF]

open access: yesBritish Journal of Pharmacology, 2011
Most cells express a panel of different G protein‐coupled receptors (GPCRs) allowing them to respond to at least a corresponding variety of extracellular ligands. In order to come to an integrative well‐balanced functional response these ligand–receptor pairs can often cross‐regulate each other.
Vischer, H.F.   +3 more
openaire   +2 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Temperature compensation of digital inertial sensors [PDF]

open access: yes, 1974
Heaters for thermal stabilization are unnecessary when analog dc voltage provided by gyroscope temperature sensor is used to change outputs to compensate for temperature variations.
Hand, P. J.
core   +1 more source

Rejoinder: Classifier Technology and the Illusion of Progress

open access: yes, 2006
Rejoinder: Classifier Technology and the Illusion of Progress [math.ST/0606441]Comment: Published at http://dx.doi.org/10.1214/088342306000000079 in the Statistical Science (http://www.imstat.org/sts/) by the Institute of Mathematical Statistics ...
Hand, David J.
core   +2 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Inferior stabilization of cementless compared with cemented dual-mobility cups in elderly osteoarthrosis patients: a randomized controlled radiostereometry study on 60 patients with 2 years’ follow-up

open access: yesActa Orthopaedica, 2020
Background and purpose — Elderly patients may benefit from a dislocation low-risk dual-mobility (DM) articulation in total hip arthroplasty, but the best cup fixation method is unknown.
Steffan Tabori-Jensen   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

MicroRNA-421 affects the chemotaxis of monocytes via MCP-1, and regulates the local immune responses in injured cartilage site of elbow joint of upper limbs

open access: yesBiotechnology & Biotechnological Equipment, 2020
The aim of the present study was to determine the expression of MCP-1 in injured cartilage tissues, peripheral blood and synovial fluid from patients with cartilage injury of elbow joint of upper limbs, and try to understand its relationship with ...
Feng Zhu, Jie Yin, Junjie Li, Jianbo Xue
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

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