Results 51 to 60 of about 8,919,752 (327)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Prediction of pilot induced oscillations [PDF]
INCAS Bulletin, 2011 An important problem in the design of flight-control systems for aircraft under pilotedcontrol is the determination of handling qualities and pilot-induced oscillations (PIO) tendencieswhen significant nonlinearities exist in the vehicle description. The
Valentin PANĂ
doaj +1 more source
A summary of rotorcraft handling qualities research at NASA Ames Research Center [PDF]
, 1984 The objectives of the rotorcraft handling qualities research program at Ames Research Center are twofold: (1) to develop basic handling qualities design criteria to permit cost effective design decisions to be made for helicopters, and (2) to obtain ...
Chen, R. T.
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Managing non‐functional requirements in agile software development
IET Software, 2022 Non‐functional requirements define qualities of the software system that ensure effectiveness while embedding any constraints and restrictions on the design.
Scarlet Rahy, Julian M. Bass
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Demonstrating NISQ era challenges in algorithm design on IBM’s 20 qubit quantum computer
AIP Advances, 2020 As superconducting qubits continue to advance technologically, the realization of quantum algorithms from theoretical abstraction to physical implementation requires knowledge of both quantum circuit construction as well as hardware limitations.
Daniel Koch +4 more
doaj +1 more source
Exploratory piloted simulator study of the effects of winglets on handling qualities of a representative agricultural airplane [PDF]
The effects on handling qualities of adding winglets to a representative agricultural aircraft configuration during swath-run maneuvering were evaluated.
Brown, P. W., Ogburn, M. E.
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source