Results 61 to 70 of about 8,919,752 (327)

Robust control of longitudinal flight with handling qualities constraints [PDF]

, 2007
Classical flight control systems are still widely used in industry because of acquired experience and good understanding of their structure. Nevertheless, with more stringent constraints, it becomes difficult to easily fulfill all the criteria with ...
Akhrif, Ouassima, Bérard, Caroline, Saussié, David, Saydy, Lahcen   +3 more
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Applications of flight control system methods to an advanced combat rotorcraft [PDF]

Advanced flight control system design, analysis, and testing methodologies developed at the Ames Research Center are applied in an analytical and flight test evaluation of the Advanced Digital Optical Control System (ADOCS) demonstrator.
Fletcher, Jay W., Morris, Patrick M., Tischler, Mark B., Tucker, George T.   +3 more
core   +1 more source

Validation and Verification of Aircraft Control Software for Control Improvement [PDF]

, 2007
Validation and Verification are important processes used to ensure software safety and reliability. The Cooper-Harper Aircraft Handling Qualities Rating is one of the techniques developed and used by NASA researchers to verify and validate control ...
Pham, Thien-Anh
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Flight evaluation of advanced control systems and displays on a general aviation airplane [PDF]

A flight-test program was conducted to determine the effect of advanced flight control systems and displays on the handling qualities of a light twin-engined airplane.
Barber, M. R., Enevoldson, E. K., Loschke, P. C., Mcmurtry, T. C.   +3 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Handling Quality of Woven Fabrics

Journal of the Textile Machinary Society, 1961
目的 織物のハンドリングをあらわす特性として, 硬さ, 厚さを選び, これらが人の感覚にどのように感ずるかを調べ合せて物理的特性との関連性を考察し, 織物のハンドリングを評価するための基礎資料をうる.成果濃度のわずかに異なる薄のり液でのり付した綿ブロードについて官能検査によって硬さ, 厚さについて実験した結果を解析してつぎの結果をえた.(1) 硬さのようなわかりやすい特性については判断は比較的よく一致する.(2) 官能による判定は他の特性に大きく影響されるものがある.本実験では厚さが硬さによって左右される結果となっているように, ハンドリングの評価には判定を誤まる要素が多くあると考えられる.(3) 本実験では硬さはハートループおよびカンチレバと比較的一致しているが ...
H. Nakazato, I. Kageyama
openaire   +2 more sources

Rotorcraft handling-qualities design criteria development [PDF]

Joint NASA/Army efforts at the Ames Research Center to develop rotorcraft handling-qualities design criteria began in earnest in 1975. Notable results were the UH-1H VSTOLAND variable stability helicopter, the VFA-2 camera-and-terrain-board simulator ...
Aiken, Edwin W., Chen, Robert T. N., Key, David L., Lebacqz, J. Victor   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source