Results 71 to 80 of about 2,353 (183)

Hantavirus cardiopulmonary syndrome

The Southwest Journal of Medicine
Hantavirus infections are a rare group of zoonotic infections with a global distribution. In the United States the most common presentation is Hantavirus cardiopulmonary syndrome, characterized by an acute febrile illness with bilateral interstitial pulmonary infiltrates and cardio-respiratory compromise. Fatality nears 40% in U.S.
Donna Kizziar, Javier Dieguez
openaire   +1 more source

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

The FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhoufu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Fan Luo   +16 more
wiley   +1 more source

Animal Models for the Study of Rodent‐Borne Hemorrhagic Fever Viruses: Arenaviruses and Hantaviruses

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
Human pathogenic hantaviruses and arenaviruses are maintained in nature by persistent infection of rodent carrier populations. Several members of these virus groups can cause significant disease in humans that is generically termed viral hemorrhagic fever (HF) and is characterized as a febrile illness with an increased propensity to cause acute ...
Joseph W. Golden, Christopher D. Hammerbeck, Eric M. Mucker, Rebecca L. Brocato, Kevin M. Coombs   +4 more
wiley   +1 more source

Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2012
Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents.
William Marciel de Souza, Alex Martins Machado, Geonildo Rodrigo Disner, Everton Boff, Aline Rafaela da Silva Rodrigues Machado, Michelly de Padua, Luiz Tadeu Moraes Figueiredo, Gustavo Borba de Miranda   +7 more
doaj   +1 more source

Hantavirus Infections in Light of Current Knowledge [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2017
Hantavirus is an enveloped virus with an RNA genome comprised of three negative-sense, single-stranded segments and belongs to the genus Hantavirus in family Bunyaviridae.
Selçuk KAYA
doaj   +1 more source

Expression of a hantavirus N protein and its efficacy as antigen in immune assays [PDF]

Hantavirus cardiopulmonary syndrome (HCPS) has been recognized as an important public heath problem. Five hantaviruses associated with HCPS are currently known in Brazil: Juquitiba, Araraquara, Laguna Negra-like, Castelo dos Sonhos, and Anajatuba viruses.
AQUINO, V.H., BORGES, A.A., FIGUEIREDO, G.G., FIGUEIREDO, L.T.M., MORELI, M.L., SOUZA, R.L.M.   +5 more
core   +1 more source

Gastrointestinal Tract As Entry Route for Hantavirus Infection [PDF]

, 2017
Background: Hantaviruses are zoonotic agents that cause hemorrhagic fevers and are thought to be transmitted to humans by exposure to aerosolized excreta of infected rodents. Puumala virus (PUUV) is the predominant endemic hantavirus in Europe.
Brocato, Rebecca L., Bücker, Roland, Hooper, Jay W., Jürgensen, Christian, Krüger, Detlev H., Perley, Casey C., Schulzke, Joerg-Dieter, Witkowski, Peter T.   +7 more
core   +2 more sources

Elevated Generation of Reactive Oxygen/Nitrogen Species in Hantavirus Cardiopulmonary Syndrome [PDF]

Journal of Virology, 2002
ABSTRACTHantavirus cardiopulmonary syndrome (HCPS) is a life-threatening respiratory disease characterized by profound pulmonary edema and myocardial depression. Most cases of HCPS in North America are caused by Sin Nombre virus (SNV), which is carried asymptomatically by deer mice (Peromyscus maniculatus).
Ian C, Davis, Allan J, Zajac, Kurt B, Nolte, Jason, Botten, Brian, Hjelle, Sadis, Matalon   +5 more
openaire   +2 more sources

Unveiling the impacts of land use on the phylogeography of zoonotic New World Hantaviruses

Ecography, Volume 2024, Issue 10, October 2024.
Billions of genomic sequences and records of species occurrence are available in public repositories (e.g. National Center for Biotechnology Information, NCBI and the Global Biodiversity Information Facility, GBIF). By implementing analytical tools from different scientific disciplines, data mining these databases can aid in the global surveillance of ...
Gabriel E. García‐Peña, André V. Rubio   +1 more
wiley   +1 more source

Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]

, 2016
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O., Johansson, M.U., Kunz, S., Rothenberger, S., Torriani, G.   +4 more
core   +2 more sources