Results 101 to 110 of about 21,916 (222)

Molecular dynamics simulations of hapten binding to structural models of 2-phenyloxazolone antibodies

, 1992
Structural models of an anti-2-phenyloxazolone (Ox1) idiotype and its high-affinity variant NQ22/18.7 were constructed by computer-aided molecular modeling using known structures of highly homologous immunoglobulins as templates.
Teleman, Olle, Holm, Liisa, Laaksonen, Leif, Hoffren, Anna-Marja, Teeri, Tuula   +4 more
core   +1 more source

Verfahren zur Charakterisierung und Selektion Hapten-spezifischer Hybridomazellen und Herstellung hochaffiner monoklonaler anti-Hapten-Antikörper

, 2016
Die vorliegende Erfindung liegt auf dem Gebiet der Herstellung hochaffiner anti-Hapten-Antikörper. Ferner befasst sich die vorliegende Erfindung mit einem Markierungsverfahren zur durchflußzytometrischen Charakterisierung und Selektion Hapten ...
Kuhne, Maren, Schneider, Rudolf
core  

General scheme for addition of different linkers to Hapten 7.

, 2013
General scheme for addition of different linkers to Hapten 7.
Heather L. Davis (465261), Phil White (465256), James R. Merson (465260), Lyn H. Jones (465244), Alan D. Brown (465249), Michelle Benoit (465258), David C. Pryde (353590), Yvonne Wharton (465254), Jotham W. Coe (465250), Ningli Zhang (465257), David P. Gervais (465245), David C. Blakemore (465247), Rebecca Glen (465253), Matthew Badland (465251), Gavin J. Miller (465255), David M. Beal (465252), Michael J. McCluskie (465262), David R. Stead (465246), Matthew D. Selby (465248), Karen Robertson (465259)   +19 more
core   +1 more source

A focused antibody library for improved hapten recognition

, 2005
The topography of the antigen-binding site as well as the number and the positioning of the antigen contact residues are strongly correlated with the size of the antigen with which the antibody interacts.
Ohlin, Mats, Persson, Helena, Lantto, Johan   +2 more
core   +1 more source

Modification and expulsion of keratins by human epidermal keratinocytes upon hapten exposure in vitro.

, 2011
Allergic contact dermatitis is the most prevalent form of human immunotoxicity. It is caused by reactive low molecular weight chemicals, that is, haptens, coming in contact with the skin where hapten-peptide complexes are formed, activating the immune ...
Ericson, Marica B,, Ericson, Marica B, Charlotte A. Jonsson, Stenfeldt, Anna-Lena, Simonsson, Carl,, Anna-Lena Stenfeldt, Marica B. Ericson, Sofia I. Andersson, Bergström, Jörgen,, Jörgen Bergström, Broo, Kerstin S, Stenfeldt, Anna-Lena,, Jonsson, Charlotte A, Andersson, Sofia, Kerstin S. Broo, Andersson, Sofia,, Bauer, Brigitte, Bauer, Brigitte,, Simonsson, Carl, Carl Simonsson, Jonsson, Charlotte A,, Bergstr\uf6m, J\uf6rgen, Brigitte Bauer   +22 more
core   +1 more source

Induction of antibodies against a peptide hapten does not require covalent linkage between the hapten and a class II presentable T helper peptide

, 1991
Following immunization with a complex antigen, a B cell internalizes this antigen through an interaction between its surface immunoglobulins and an epitope of the antigen.
Maria‐Pilar Civeira, Sarobe, P. (Pablo), Gullon, A. (Arturo), Lasarte, J.J. (Juan José), Golvano, J.J. (José Javier), Francisco Borrás‐Cuesta, Prieto, J. (Jesús), Juan‐José Lasarte, José Golvano, Jesús Prieto, Borras-Cuesta, F. (Francisco), Pablo Sarobe, Arturo Gullón, Civeira, M.P. (María Pilar)   +13 more
core   +1 more source

Anti-hapten antibodies in response to skin sensitization.

, 2015
Whereas T lymphocyte (T cell) activation is the key event in the acquisition of skin sensitization and subsequent elicitation of allergic contact dermatitis, the humoral component of immune responses to organic contact allergens has received little ...
Helen Singleton, Gavin Maxwell, Williams, Jason, Kimber, Ian, Jason Williams, Maxwell, Gavin, Gellatly, Nichola, Ian Kimber, Rebecca J. Dearman, Amy Popple, Singleton, Helen, Popple, Amy, Dearman, Rebecca J, Nichola Gellatly, Friedmann, Peter S, Peter S. Friedmann   +15 more
core   +2 more sources

Does hapten exposure predispose to atopic disease? The hapten-atopy hypothesis

, 2009
Contact allergy data indicates that atopics have heightened oral tolerance to haptens (chemical allergens). We speculate here, that artificially increased oral exposure to chemicals compete with dietary proteins for the development of oral tolerance ...
Kimber, I., White, J. M L, Basketter, D. A., McFadden, J. P.   +3 more
core   +1 more source

Preferential production of IgG2 anti-hapten antibody by immunization with hapten-conjugated Escherichia coli

, 1975
It is well-known that immunization of guinea pigs with hapten-protein conjugates induces concomitant production of IgGl and IgG2 anti-hapten antibodies.
Kiyoshi Furuichi, Jiro Koyama
core  

Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM₁₉₇ Carriers

, 2015
Vaccines against drugs of abuse have induced antibodies in animals that blocked the biological effects of the drug by sequestering the drug in the blood and preventing it from crossing the blood-brain barrier.
Kenner C. Rice (1582948), Rashmi Jalah (513403), Fuying Li (795082), Joshua F. G. Antoline (1582939), Arthur E. Jacobson (1321668), Carl R. Alving (1582951), Oscar B. Torres (1582942), Zoltan Beck (368735), Alexander V. Mayorov (1582945), Gary R. Matyas (368738), Jeffrey R. Deschamps (614211)   +10 more
core   +1 more source