Results 101 to 110 of about 19,297 (229)

Formaldehyde Emissions From 2‐Octyl Cyanoacrylate: Quantified Risk for Allergic Contact Dermatitis

open access: yesContact Dermatitis, Volume 94, Issue 6, Page 635-644, June 2026.
This study found that 2‐octyl cyanoacrylate skin adhesives release formaldehyde at levels up to 8.4× above EPA dermal thresholds and up to 2.41× above NIOSH airborne limits, producing exposures sufficient to provoke allergic and irritant contact dermatitis in patients.
Daniel S. Rouhani   +6 more
wiley   +1 more source

Verfahren zur Charakterisierung und Selektion Hapten-spezifischer Hybridomazellen und Herstellung hochaffiner monoklonaler anti-Hapten-Antikörper

open access: yes, 2016
Die vorliegende Erfindung liegt auf dem Gebiet der Herstellung hochaffiner anti-Hapten-Antikörper. Ferner befasst sich die vorliegende Erfindung mit einem Markierungsverfahren zur durchflußzytometrischen Charakterisierung und Selektion Hapten ...
Kuhne, Maren, Schneider, Rudolf
core  

Induction of antibodies against a peptide hapten does not require covalent linkage between the hapten and a class II presentable T helper peptide

open access: yes, 1991
Following immunization with a complex antigen, a B cell internalizes this antigen through an interaction between its surface immunoglobulins and an epitope of the antigen.
Maria‐Pilar Civeira   +13 more
core   +1 more source

Efficacy, but Not Antibody Titer or Affinity, of a Heroin Hapten Conjugate Vaccine Correlates with Increasing Hapten Densities on Tetanus Toxoid, but Not on CRM197 Carriers

open access: yes, 2015
Vaccines against drugs of abuse have induced antibodies in animals that blocked the biological effects of the drug by sequestering the drug in the blood and preventing it from crossing the blood-brain barrier.
Kenner C. Rice (1582948)   +10 more
core   +1 more source

Gamma delta T cells recognize haptens and mount a hapten-specific response

open access: yeseLife, 2014
The ability to recognize small organic molecules and chemical modifications of host molecules is an essential capability of the adaptive immune system, which until now was thought to be mediated mainly by B cell antigen receptors.
Xun Zeng   +6 more
doaj   +1 more source

Odorant and hapten responses by primary lymphocytes and cell lines.

open access: yes, 2016
Odorant and hapten responses by primary lymphocytes and cell lines.
Camille Grandclément (2559823)   +3 more
core   +1 more source

Generation of hapten-specific recombinant antibodies: antibody phage display technology: a review

open access: yesVeterinární Medicína, 2005
Production of antibodies has been revolutionized by the development of modern molecular biology methods for the expression of recombinant DNA. Phage display technology represents one of the most powerful tools for production and selection of recombinant ...
J. Brichta, M. Hnilova, T. Viskovic
doaj   +1 more source

Does hapten exposure predispose to atopic disease? The hapten-atopy hypothesis

open access: yes, 2009
Contact allergy data indicates that atopics have heightened oral tolerance to haptens (chemical allergens). We speculate here, that artificially increased oral exposure to chemicals compete with dietary proteins for the development of oral tolerance ...
Kimber, I.   +3 more
core   +1 more source

Investigating Hapten Clustering as a Strategy to Enhance Vaccines against Drugs of Abuse

open access: yes, 2015
Vaccines for drugs of abuse have yet to achieve full clinical relevance, largely due to poor/inconsistent immune responses in patients. The use of multivalent scaffolding as a means to tailor drug–hapten density and clustering was examined in the context
Karen C. Collins (1311750)   +1 more
core   +1 more source

Modification and Expulsion of Keratins by Human Epidermal Keratinocytes upon Hapten Exposure in Vitro

open access: yes, 2015
Allergic contact dermatitis is the most prevalent form of human immunotoxicity. It is caused by reactive low molecular weight chemicals, that is, haptens, coming in contact with the skin where hapten−peptide complexes are formed, activating the immune ...
Brigitte Bauer (1277646)   +7 more
core   +1 more source

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