Results 111 to 120 of about 19,297 (229)

Preferential production of IgG2 anti-hapten antibody by immunization with hapten-conjugated Escherichia coli

open access: yes, 1975
It is well-known that immunization of guinea pigs with hapten-protein conjugates induces concomitant production of IgGl and IgG2 anti-hapten antibodies.
Kiyoshi Furuichi, Jiro Koyama
core  

Characterization of Primary T Helper Cell Activation and T Helper Cell Lines Stimulated by Hapten-modified, Cultured Langerhans Cells

open access: yes, 1989
It has recently been shown that hapten-modified cultured Langerhans cells are able to activate small resting syngeneic L3T4+ T helper cells from nonsensitized animals.
Yokoyama, Wayne M.   +5 more
core   +1 more source

Development of Hapten-Linked Microimmunoassays on Polycarbonate Discs

open access: yes, 2016
An amino-modified polycarbonate surface of compact discs is used to link haptens covalently and directly as an alternative to the classic protein−hapten conjugate adsorption coating strategy employed in immunoassays.
Jesús Tamarit-López (2134783)   +4 more
core   +1 more source

A Conjugate Vaccine Using Enantiopure Hapten Imparts Superior Nicotine-Binding Capacity

open access: yes, 2016
A leading nicotine conjugate vaccine was only efficacious for one-third of clinical trial participants, likely due in part to its use of racemic nicotine hapten, (±)-3′-AmNic.
Marc R. Azar (1684675)   +5 more
core   +1 more source

Novel mouse model of colitis characterized by hapten-protein visualization

open access: yes, 2010
Trinitrobenzene sulfonic acid (TNBS) and oxazolone are used to induce colitis for the investigation of inflammatory reactions in the colon. Although these chemicals are presumed to bind proteins in the colonic mucosa and then induce colitis as haptens ...
Osamu Watanabe   +4 more
core   +1 more source

Dendritic cells, hapten presentation and lymph node cell activation following cutaneous sensitization in the mouse [PDF]

open access: yes
Lymph node cells from mice which have undergone primary cutaneous sensitization (responder cells) were cultured with either in vitro haptenated cells or hapten-bearing dendritic cells from hapten sensitized mice.
Jones, David Allan
core  

Anti-hapten antibodies in response to skin sensitization.

open access: yes, 2015
Whereas T lymphocyte (T cell) activation is the key event in the acquisition of skin sensitization and subsequent elicitation of allergic contact dermatitis, the humoral component of immune responses to organic contact allergens has received little ...
Helen Singleton   +15 more
core   +1 more source

Fundamentals of hapten-protein conjugate synthesis to obtain high-quality antibodies for analysis of food and environmental contaminants

open access: yes, 2017
Developing immunoassays for detecting natural and synthetic contaminants in foods and environments have raised great attention. Thus, tailoring the structure of the conjugates via hapten design has been regarded as an original and efficient way to obtain
Li, Peiwu   +4 more
core   +1 more source

Reactivation of hapten-induced colitis and its prevention by anti-inflammatory drugs

open access: yes, 1995
Administration of a hapten together with a barrier breaker, such as ethanol, into the colon of a rat results in extensive mucosal injury and inflammation that bears some similarity to the colonic inflammation characterizing inflammatory bowel disease in
C. B. Appleyard, J. L. Wallace
core   +1 more source

Discovery of Hapten-Specific scFv from a Phage Display Library and Applications for HER2-Positive Tumor Imaging

open access: yes, 2015
In this study, an anti-hapten antibody (single chain Fv, scFv) against a hapten probe was developed as a unique reporter system for molecular imaging or therapy.
Xiaolei Wang (139592)   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy