Results 91 to 100 of about 21,916 (222)

Protective and Pathogenic Antibodies to Citrullinated Antigens

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Autoimmune diseases start years before clinical onset. In rheumatoid arthritis (RA), autoantibodies to citrullinated proteins (ACPA) and to modified IgG (rheumatoid factors, RF) can be detected many years before the inflammatory attack on cartilaginous joints. It has been assumed that these antibodies are pathogenic.
Outi Sareila, Yibo He, Zhongwei Xu, Changrong Ge, Erik Lönnblom, Rikard Holmdahl   +5 more
wiley   +1 more source

Delayed Hypersensitivity to Hapten-Protein Conjugates. III. Saccharides as Haptens.

Experimental Biology and Medicine, 1963
SummaryConjugates of monosaccharide and disaccharide haptens to protein have been found to function adequately in the induction and elicitation of delayed hypersensitivity reactions in the guinea pig. The characteristics of these delayed responses paralleled those observed with other ionic and nonpolar haptens.
F, BOREK, A M, SILVERSTEIN, P G, GELL
openaire   +2 more sources

Germinal Center Selection and Plasma Cell Differentiation

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Germinal centers (GCs) are specialized microenvironments in which B cells undergo affinity maturation through iterative cycles of somatic hypermutation, proliferation and selection, generating antibodies with improved antigen‐binding properties.
Adrien Sprumont, Oliver Bannard
wiley   +1 more source

Plasma Cell Selection and Migration in the Establishment of Long‐Lived Antibody Responses

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT As B cells are activated and differentiate into plasma cells, they execute migration programs that allow them to traffic within secondary lymphoid tissues and reach the bone marrow, where they can mature as long‐lived plasma cells. Recent studies have revealed mechanisms underlying not only affinity‐driven but also isotype‐driven plasma cell ...
Wataru Ise, Kazuhiro Suzuki, Tomohiro Kurosaki   +2 more
wiley   +1 more source

Characterization of Primary T Helper Cell Activation and T Helper Cell Lines Stimulated by Hapten-modified, Cultured Langerhans Cells [PDF]

, 1989
It has recently been shown that hapten-modified cultured Langerhans cells are able to activate small resting syngeneic L3T4+ T helper cells from nonsensitized animals.
Yokoyama, Wayne M., Conrad Hauser, Wayne M. Yokoyama, Stephen I. Katz, Katz, Stephen I., Hauser, Conrad   +5 more
core   +1 more source

Determination of Morphine in Human Urine by the Novel Competitive Fluorescence Immunoassay

Journal of Analytical Methods in Chemistry, 2019
A competitive fluorescence immunoassay for the identification and quantification of morphine has been developed on the basis of hapten-coated plate format. Hapten was prepared through covalent conjugating a morphine derivative with albumin bovine. In the
Jie Cao, Xiao-Ying Chen, Wu-Rong Zhao
doaj   +1 more source

Preparo e avaliação do imunoconjugado para atrazina

Eclética Química, 2018
In order to study the affinity reaction between the anti-atrazine antibody and atrazine, an enzyme was incorporated, as a marker, to an atrazine carboxylic derivative. The hapten and conjugate were synthesized and characterized by MS, IR and NMR.
Carla dos Santos Riccardi, Ângela Regina Araújo, Hideko Yamanaka   +2 more
doaj   +1 more source

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6380-6394, 30 August 2026.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

Unveil the molecular recognition mechanisms of triazine haptens and monoclonal antibodies: Establishing ic‐ELISA methods for triazine herbicide analysis in tea

Food Safety and Health
This study introduced two triazine haptens (with 0 or 1 carbon connecting arms at nonisopropyl positions) and developed two heterologous indirect competitive enzyme‐linked immunosorbent assay (ic‐ELISA) methods.
Lingyuan Xu, A. M. Abd El‐Aty, Peipei Li, Jia Li, Jing Zhao, Xingmei Lei, Song Gao, Yun Zhao, Yongxin She, Fen Jin, Jing Wang, Bruce D. Hammock, Maojun Jin   +12 more
doaj   +1 more source

Monoclonal antibody usage strategies for natural products in traditional chinese medicine

World Journal of Traditional Chinese Medicine, 2017
Monoclonal antibodies (MAbs) against natural products with low-molecular weights have become an important tool when combined with other analytical systems.
Yukihiro Shoyama
doaj   +1 more source