Results 71 to 80 of about 19,297 (229)
On the structure of cytolipin R, a ceramide tetrahexoside hapten from rat lymphosarcoma
Cytolipin R, a ceramide tetrahexoside isolated from rat lymphosarcoma, was studied by sequential hydrolysis with specific glycosidases which revealed the anomeric configurations of the glycosidic bonds.
R. Laine +4 more
doaj +1 more source
This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen +7 more
wiley +1 more source
Probing the Effects of Hapten Stability on Cocaine Vaccine Immunogenicity
Judicious hapten design has been shown to be of importance when trying to generate a viable vaccine against a drug of abuse. Hapten design has typically been predicated upon faithfully emulating the unique chemical architecture that each drug presents ...
Xiaoqing Cai (288275) +6 more
core +1 more source
Targeted siRNA Delivery and mRNA Knockdown Mediated by Bispecific Digoxigenin-binding Antibodies
Bispecific antibodies (bsAbs) that bind to cell surface antigens and to digoxigenin (Dig) were used for targeted small interfering RNA (siRNA) delivery. They are derivatives of immunoglobulins G (IgGs) that bind tumor antigens, such as Her2, IGF1-R, CD22,
Britta Schneider +22 more
doaj +1 more source
Immunological identity of brucella native hapten, polysaccharide B, and yersinia enterocolitica serotype 9 native hapten [PDF]
Yersinia enterocolitica serotype 9 contained an antigenic component giving a reaction of total identity with Brucella native hapten and polysaccharide B. This component was present in a phenol-water extract (fraction 5; M. Redfearn, Ph.D.
Moriyon, I. (Ignacio) +2 more
core
Autoimmunity and Periodontitis
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
Structures of different linker-modified nicotine hapten.
Structures of different linker-modified nicotine hapten.
Heather L. Davis (465261) +19 more
core +1 more source
Delayed Hypersensitivity to Hapten-Protein Conjugates. III. Saccharides as Haptens.
SummaryConjugates of monosaccharide and disaccharide haptens to protein have been found to function adequately in the induction and elicitation of delayed hypersensitivity reactions in the guinea pig. The characteristics of these delayed responses paralleled those observed with other ionic and nonpolar haptens.
F, BOREK, A M, SILVERSTEIN, P G, GELL
openaire +2 more sources
Metal Sensitization in Patients That Underwent Patch Test Pre and Post‐Implant Exposure
Sensitization to metals was similar in pre‐implant and post‐implant patients. Women with jewellery allergy are at higher risk to have a patch test positive to metals. Post‐implant testing in case of contact dermatitis could be helpful to identify culprit allergens. ABSTRACT Background Sensitization to metals can cause allergic symptoms in subjects that
Nicholas Zampa +5 more
wiley +1 more source
Gallic acid (GA) is closely related to the quality of herbal medicines and other agricultural products. In order to facilitate the rapid detection of GA, we developed a monoclonal antibody-based ic-ELISA method.
Jiajing Duan +6 more
doaj +1 more source

