Results 61 to 70 of about 21,916 (222)
Pre‐Seasonal Treatment With Recombinant Carrier‐Based Birch Vaccine Improves Birch Pollen Allergy
Allergy, EarlyView.We conducted a two stage SCIT trial with GNR‐127 containing a recombinant fusion protein consisting of Bet v 1 and Mal d 1‐derived peptides fused to PreS from HBV. Stage 1 identified two safe maximum tolerated doses (40 μg and 80 μg). In the following Stage 2, five preseasonal injections were well tolerated, induced dose‐dependent allergen‐specific IgG,
Musa R. Khaitov +43 more
wiley +1 more source
Molecules, 2019 The structure of hapten determines the performance of the antibody and the corresponding detection method. A new type of antigen was designed and synthesized to expose the spatial and characteristic structure of dinotefuran molecule, and a type of high ...
Fangfang Zhao, Jingkun Liu, Jinhui Luo
doaj +1 more source
An immunoassay for dibutyl phthalate based on direct hapten linkage to the polystyrene surface of microtiter plates. [PDF]
PLoS ONE, 2011 BACKGROUND: Dibutyl phthalate (DBP) is predominantly used as a plasticizer inplastics to make them flexible. Extensive use of phthalates in both industrial processes and other consumer products has resulted in the ubiquitous presence of phthalates in the
Chenxi Wei +6 more
doaj +1 more source
Contact Dermatitis, EarlyView.Finn Chamber AQUA (FCA) detects significantly higher contact allergy prevalences to linalool hydroperoxides (7.0% vs. 5.1% FC) and limonene hydroperoxides (7.8% vs. 3.0% FC, 3.8% IQ) than Finn Chamber (FC) or IQ Ultra (IQ) in 629 dermatitis patients; chamber choice is therefore crucial for diagnostics.
Henrik Luu +4 more
wiley +1 more source
Nicotine and hapten structures.
, 2013 The thioacetate of Hapten 8 was deprotected to the thiol for coupling with DT.
Heather L. Davis (465261) +19 more
core +1 more source
Case Reports in Dermatology, 2021 Contact immunotherapy with several sensitizing chemicals such as diphenylcyclopropenone (DPCP) or squaric acid dibutyl ester (SADBE) have been used for the treatment of recalcitrant or multiple warts. Here, we report a case of multiple verrucae vulgaris (
Gyohei Egawa +2 more
doaj +1 more source
Contact Dermatitis, EarlyView.This study identified multiple areas for improvement in the regulatory risk assessment process. Conclusions based on predictive sensitization data should be made with caution, read‐across data from known sensitizers should be utilized, and epidemiological and patient threshold data should be prioritized in decision‐making.
Mathias Krogh Pedersen +7 more
wiley +1 more source
Contact Dermatitis, EarlyView.A case series of eight patients with allergic otitis externa from contact allergy to hearing aid ear moulds is presented. All were patch test positive to tetrahydrofurfuryl methacrylate and three to isobornyl acrylate. It is postulated that these are likely relevant allergens present in such devices. ABSTRACT Background Allergic contact dermatitis from
Norbertus A. Ipenburg +2 more
wiley +1 more source
Modulating Cocaine Vaccine Potency through Hapten Fluorination
, 2016 Cocaine addiction is a long-lasting relapsing illness characterized by cycles of abuse, abstinence, and reinstatement, and antibody-based therapies could be a powerful therapeutic approach. Herein, we explored the possibility of using halogenated cocaine
Kyoji Tsuchikama (1988068) +2 more
core +1 more source
Cutaneous drug hypersensitivity : Immunological and genetic perspective
Indian Journal of Dermatology, 2011 Drug hypersensitivity is an unpredictable, immunologically mediated adverse reaction, clustered in a genetically predisposed individual. The role of "hapten concept" in immune sensitization has recently been contested by the "pharmacological interaction"
Kisalay Ghosh +3 more
doaj +1 more source