Results 101 to 110 of about 5,135,844 (257)
Systematics validation of a software hardening framework
, 2015 This master thesis discusses the application of a fault injection testing methodology to robust programs. The objective was to find and implement a fault injection-based solution that allows to evaluate the robustness of programs under tests against a ...
Vermeylen, Alex
core
Deriving Framework Usages Based on Behavioral Models [PDF]
, 2010 One of the critical issue in framework-based software development is a huge introduction cost caused by technical gap between developers and users of frameworks.
KOBAYASHI, Takashi +2 more
core
Research on the Temperature Field in Laser Hardening
, 2006 Temperature field in the laser hardening process was numerically simulated by MSC.Marc software. The influence of energy density on laser hardening effect is analyzed.
Su YP +5 more
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Al-Driven Resilience and Risk Analysis in Disaster-Prone Transport Networks
IEEE AccessUrban transport systems are increasingly susceptible to cascading failures, necessitating advanced methods for risk identification and mitigation. This paper presents a multi-modal risk embedding framework integrating $\ell _{2,1}$ -regularized feature ...
Yiming Wang
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Soil plasticity with a different porosity
MATEC Web of Conferences, 2017 The model of soils with different porosity in the framework of the associated theory of plasticity is presented The single analytical function describes the loading surface in the stress space.
Klovanych Sergii, Malyszko Leszek
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source