Results 121 to 130 of about 3,578,042 (213)

Reverse spin bias: preliminary observations of reporting bias in medical systematic reviews

open access: yesResearch Integrity and Peer Review
Background While conducting an umbrella review of e-cigarettes for smoking cessation, we observed that in many instances, systematic review authors reported findings favorable to the treatment, yet they declined to recommend it or recommended against it ...
Renée O’Leary   +2 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Ana Liffey Drug Project to provide harm reduction services at Electric Picnic.

open access: yes, 2018
Volunteers from Ana Liffey Drug Project will be leading the drug specific interventions at Electric Picnic this year providing harm reduction services.....
McGoran, Peter
core  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Sites of resistance’: an online ethnography of harm reduction work in community drug treatment services [PDF]

open access: yes
This PhD thesis is an online ethnography that examines how harm reduction activists within community drug treatment services negotiate the ideological tension posed when practising harm reduction work within in an institutional environment driven by the ‘
Phillips, A.
core  

Methadone clinic staff perceptions of trauma-informed and patient-centered care: the role of individual staff characteristics

open access: yesAddiction Science & Clinical Practice
Background U.S. policy intervention to increase methadone treatment accommodations during COVID did not result in national adoption of the new patient-centered treatment practices.
Beth E. Meyerson   +10 more
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Harm reduction in Bern: from outreach to heroin maintenance

open access: yes, 1995
In Switzerland, harm-reduction programs have the support of the national government and many localities, in congruence with much of the rest of Europe and in contrast with the United States, and take place in public settings.
Haemmig, RB
core  

Decentralized HIV testing: comparing peer and mail-based distribution strategies to improve the reach of HIV self-testing among people who use drugs in Florida

open access: yesHarm Reduction Journal
Introduction People who use drugs (PWUD) are at increased risk for HIV infection. HIV self-testing (HIVST) is a promising method for identifying new infections, but optimal distribution strategies remain understudied.
William H. Eger   +7 more
doaj   +1 more source

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