Results 41 to 50 of about 1,956 (188)

Ueber Harmin und Harmalin [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft, 1885
n ...
Fischer, Otto, Täüber, Ernst
openaire   +2 more sources

Mapping BOLD Activation by Pharmacologically Evoked Tremor in Swine

open access: yesFrontiers in Neuroscience, 2019
Harmaline-induced tremor is one of the most commonly utilized disease models for essential tremor (ET). However, the underlying neural networks involved in harmaline-induced tremor and the degree to which these are a representative model of the ...
Jeyeon Lee   +11 more
doaj   +1 more source

Multi-Target Mechanisms of Moroccan Aphrodisiac Plants: An Integrative Computational and Phytochemical Investigation. [PDF]

open access: yesFood Sci Nutr
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200 
Elrherabi A   +8 more
europepmc   +2 more sources

Development of a mechanism-based pharmacokinetic/pharmacodynamic model to characterize the thermoregulatory effects of serotonergic drugs in mice

open access: yesActa Pharmaceutica Sinica B, 2016
We have shown recently that concurrent harmaline, a monoamine oxidase-A inhibitor (MAOI), potentiates serotonin (5-HT) receptor agonist 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT)-induced hyperthermia.
Xi-Ling Jiang   +4 more
doaj   +1 more source

Comparison of intracisternally and intraperitoneally injected harmaline on body temperature and tremor in the rat [PDF]

open access: yes, 1969
Low doses of harmaline (1–10 mg/kg) injected intraperitoneally into rats caused hypothermia, while higher doses (10–30 mg/kg) induced tremor in addition to hypothermia.
J Bruinvels
core   +1 more source

Exposure Characteristics of the Analogous β-Carboline Alkaloids Harmaline and Harmine Based on the Efflux Transporter of Multidrug Resistance Protein 2

open access: yesFrontiers in Pharmacology, 2017
Harmaline and harmine occur naturally in plants and are distributed endogenously in human and animal tissues. The two β-carboline alkaloids possess potential for treating Alzheimer's disease, Parkinson's disease, depression and other central nervous ...
Shuping Li   +10 more
doaj   +1 more source

Ultrastructural and hormonal changes related to harmaline-induced treatment in Arabidopsis thaliana (L.) Heynh. root meristem [PDF]

open access: yes, 2022
Financiado para publicación en acceso aberto: Universidade de Vigo/CISUGHarmaline is an indole alkaloid with demonstrated phytotoxicity and recognized pharmacological applications.
Álvarez Rodríguez, Sara   +4 more
core   +1 more source

The Plant Alkaloid Harmaline Blocks the Voltage-Gated Sodium Channel Na<sub>v</sub>1.7: A Study Using an Automated Patch-Clamp. [PDF]

open access: yesInt J Mol Sci
The voltage-gated sodium channel Nav1.7 is essential for pain perception and is an interesting target for the development of pain-relieving substances.
Eisfeld J   +6 more
europepmc   +2 more sources

The effect of harmaline on force of contraction of the rat isolated atrium [PDF]

open access: yes, 1975
In rat isolated right atria, beating spontaneously at 30°C, harmaline 8.3 × 10-5 M slowed atrial rate and enhanced force of contraction. The velocity of development of tension (dT/dt) increased and time to peak tension was lengthened. Electrical drive of
Carpentier, Robert   +3 more
core   +1 more source

Antibacterial and Oxacillin Resistance Reversing Effect of Harmaline in Different Strains of Staphylococcus Aureus [PDF]

open access: yesAl-Anbar Medical Journal
Background: Harmaline is a naturally occurring indole alkaloid with many medicinal effects. Its antimicrobial effect against different pathogens has been reported previously.Objective: To explore the ability of harmaline to revers oxacillin resistance in
Zaid Ibraheem
doaj   +1 more source

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