Results 21 to 30 of about 3,248 (213)
Brain and Behavior, 2022 Objective Essential tremor (ET) as a neurological disorder is accompanied by cognitive and motor disturbances. Despite the high incidence of ET, the drug treatment of ET remains unsatisfactory.
Mohammad Shabani, Reyhaneh Naderi
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Cerebello-Thalamo-Cortical Network Dynamics in the Harmaline Rodent Model of Essential Tremor
Frontiers in Systems Neuroscience, 2022 Essential Tremor (ET) is a common movement disorder, characterised by a posture or movement-related tremor of the upper limbs. Abnormalities within cerebellar circuits are thought to underlie the pathogenesis of ET, resulting in aberrant synchronous ...
Kathryn Woodward +4 more
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Scientific Reports, 2023 Harmaline and harmine are naturally occurring closely related β-carboline alkaloids found in Peganum and Banisteriopsis plants. They have historical significance in traditional practices due to their potential psychoactive and therapeutic properties ...
Ahmed H. Abdelazim +2 more
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Bone marrow transplantation alters the tremor phenotype in the murine model of globoid-cell leukodystrophy [PDF]
, 2012 Tremor is a prominent phenotype of the twitcher mouse, an authentic genetic model of Globoid-Cell Leukodystrophy (GLD, Krabbe’s disease). In the current study, the tremor was quantified using a force-plate actometer designed to accommodate low-weight ...
Dearborn, Joshua T +5 more
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Cerebellar nuclei neurons display aberrant oscillations during harmaline-induced tremor
Heliyon, 2021 Summary: Essential tremor, a common, debilitating motor disorder, is thought to be caused by cerebellar malfunction. It has been shown that rhythmic Purkinje cell firing is both necessary and sufficient to induce body tremor.
Yuval Baumel, Hagar G. Yamin, Dana Cohen
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Recreational use, analysis and toxicity of tryptamines [PDF]
, 2015 The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
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Frontiers in Systems Neuroscience, 2023 Neuronal oscillations occur in health and disease; however, their characteristics can differ across conditions. During voluntary movement in freely moving rats, cerebellar nuclei (CN) neurons display intermittent but coherent oscillations in the theta ...
Yuval Baumel +2 more
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Removal of GABAA receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations [PDF]
, 2011 We investigated the behavioral significance of fast synaptic inhibition by αβγ2-type GABA(A) receptors on parvalbumin (Pv) cells. The GABA(A) receptor γ2 subunit gene was selectively inactivated in Pv-positive neurons by Cre/loxP recombination.
Leppa, E. +10 more
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Mapping BOLD Activation by Pharmacologically Evoked Tremor in Swine
Frontiers in Neuroscience, 2019 Harmaline-induced tremor is one of the most commonly utilized disease models for essential tremor (ET). However, the underlying neural networks involved in harmaline-induced tremor and the degree to which these are a representative model of the ...
Jeyeon Lee +11 more
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Cannabinoid type 1 receptor antagonism ameliorates harmaline-induced essential tremor in rat [PDF]
, 2016 Background and purpose Essential tremor (ET) is a neurological disorder with unknown etiology. Its symptoms include cerebellar motor disturbances, cognitive and personality changes, hearing and olfactory deficits.
Abbassian, Hassan +3 more
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