Results 11 to 20 of about 1,956 (188)

Role of Harmaline in Inhibiting c-Myc, Altering Molecular Typing, and Promoting Apoptosis in Triple-Negative Breast Cancer [PDF]

Breast Cancer: Targets and Therapy
Haoyi Xu,1 Yan Ma,2 Huiling Li,1 Xinyu Song,1 Yuanjing Liu,1 Zuliyaer Mierzhakenmu,1 Kang Yan,1 Rui Xu,1 Ziqian Zhao,1 Hongyi Yuan,1 Chao Dong1 1Department of Breast and Thyroid Surgery, the Third Clinical Medical College of Xinjiang Medical University ...
Xu H, Ma Y, Li H, Song X, Liu Y, Mierzhakenmu Z, Yan K, Xu R, Zhao Z, Yuan H, Dong C   +10 more
doaj   +5 more sources

Riluzole Ameliorates Harmaline-Induced Tremor in Rat [PDF]

Basic and Clinical Neuroscience, 2014
Introduction: Excessive olivo-cerebellar burst-firing occurs during harmaline-induced tremor. We hypothesized that antiglutamatergic agents would suppress harmaline tremor.
Fatemeh Rahimi Shourmasti, Iran Goudarzi, Kataneh Abrari, Mahmoud Elahdadi Salmani, Taghi Lashkarboluki   +4 more
doaj   +3 more sources

Cerebello-Thalamo-Cortical Network Dynamics in the Harmaline Rodent Model of Essential Tremor [PDF]

Frontiers in Systems Neuroscience, 2022
Essential Tremor (ET) is a common movement disorder, characterised by a posture or movement-related tremor of the upper limbs. Abnormalities within cerebellar circuits are thought to underlie the pathogenesis of ET, resulting in aberrant synchronous ...
Kathryn Woodward, Richard Apps, Marc Goodfellow, Marc Goodfellow, Nadia L. Cerminara   +4 more
doaj   +5 more sources

Harmaline Tremor: Underlying Mechanisms in a Potential Animal Model of Essential Tremor [PDF]

Tremor and Other Hyperkinetic Movements, 2012
Background: Harmaline and harmine are tremorigenic β-carbolines that, on administration to experimental animals, induce an acute postural and kinetic tremor of axial and truncal musculature.
Adrian Handforth
doaj   +3 more sources

Harmaline-Induced Tremor in Mice: Videotape Documentation and Open Questions About the Model [PDF]

Tremor and Other Hyperkinetic Movements, 2013
Background: Harmaline‐induced tremor in rodents has been extensively used as an animal model for essential tremor (ET). However, there is no visual documentation in the published literature.Methods: We injected mice subcutaneously with either 20 mg/kg of
Melody M. Cheng, Guomei Tang, Sheng-Han Kuo   +2 more
doaj   +3 more sources

Phytohormone abscisic acid elicits positive effects on harmaline‐induced cognitive and motor disturbances in a rat model of essential tremor [PDF]

Brain and Behavior, 2022
Objective Essential tremor (ET) as a neurological disorder is accompanied by cognitive and motor disturbances. Despite the high incidence of ET, the drug treatment of ET remains unsatisfactory.
Mohammad Shabani, Reyhaneh Naderi
doaj   +2 more sources

Harmaline-induced impairment of Pavlovian conditioning in the rabbit [PDF]

The Journal of Neuroscience, 1993
In this study we examined the effects of harmaline on Pavlovian conditioning of the rabbit's nictitating membrane response. The acquisition of conditioned responses was determined during a single session consisting of 120 pairings of a tone-conditioned stimulus with a corneal air puff unconditioned stimulus.
J A, Harvey, A G, Romano
openaire   +4 more sources

The Role of Hippocampal 5HT3 Receptors in Harmaline-Induced Memory Deficit [PDF]

Basic and Clinical Neuroscience, 2015
Introduction: The plethora of studies indicated that there is a cross talk relationship between harmaline and serotonergic (5-HT) system on cognitive and non-cognitive behaviors.
Mohammad Nasehi
doaj   +1 more source

In vitro anti-parasitic effect of the alkaloids harmaline and piperine on Toxoplasma gondii [PDF]

Revista Brasileira de Parasitologia Veterinária
Toxoplasma gondii is a coccidian protozoan of zoonotic importance that causes toxoplasmosis. Although the current treatments for toxoplasmosis may be associated with adverse effects and limited efficacy for different biological forms of the parasite ...
Daniele Silva Souza Carreira, Carolina Emy Sato, Waléria Borges da Silva, Thereza Cristina Borio dos Santos Calmon de Bittencourt, Silvia Lima Costa, Rosângela Soares Uzêda   +5 more
doaj   +2 more sources

Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections [PDF]

Microbial Cell Factories
Background A novel plasmid-mediated resistance–nodulation–division (RND) efflux pump gene cluster tmexCD1-toprJ1 in Klebsiella pneumoniae tremendously threatens the use of convenient therapeutic options in the post-antibiotic era, including the “last ...
Jindian Yang#, Lei Xu#, Yonglin Zhou, Minhe Cui, Dejun Liu, Jianfeng Wang, Yang Wang, Xuming Deng   +7 more
doaj   +2 more sources