Results 111 to 120 of about 6,212,855 (344)

Bone mineral density and risk of heart failure in older adults: The Cardiovascular Health Study [PDF]

, 2017
Background Despite increasing evidence of a common link between bone and heart health, the relationship between bone mineral density ( BMD ) and heart failure ( HF
Bartz, Traci M, Brown, David L, Carbone, Laura D, Chaves, Paulo H.M., Civitelli, Roberto, Fohtung, Raymond B, Kestenbaum, Bryan R, Kizer, Jorge R, Koh, William J.H., Stein, Phyllis K   +9 more
core   +2 more sources

Bias Of The Cox Model Hazard Ratio

Journal of Modern Applied Statistical Methods, 2005
In recent decades, survival analysis techniques have been extended far beyond the medical, biomedical, and reliability research areas to fields such as engineering, criminology, sociology, marketing, insurance, economics, etc. The study of survival data has previously focused on predicting the probability of response, survival, or mean lifetime, and ...
Persson, Inger, Khamis, Harry J.
openaire   +2 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Rejoinder to Letter to the Editor “The Hazards of Period Specific and Weighted Hazard Ratios”

Statistics in Biopharmaceutical Research, 2020
We would like to thank the authors of the letter (Bartlett et al. 2020) for sharing their concerns regarding reporting treatment effect under nonproportional hazards (NPH), and we respect their pos...
Ray S. Lin, Ji Lin, Satrajit Roychoudhury, Keaven M. Anderson, Tianle Hu, Bo Huang, Larry F. Leon, Jason J. Z. Liao, Rong Liu, Xiaodong Luo, Pralay Mukhopadhyay, Rui Qin, Kay Tatsuoka, Xuejing Wang, Yang Wang, Jian Zhu, Tai-Tsang Chen, Renee Iacona   +17 more
openaire   +4 more sources

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

Comorbid conditions explain the association between posttraumatic stress disorder and incident cardiovascular disease [PDF]

, 2019
Background Posttraumatic stress disorder ( PTSD ) is associated with risk of cardiovascular disease ( CVD ). Biopsychosocial factors associated with PTSD likely account for some or all of this association.
Chard, Kathleen M, Cohen, Beth E, Friedman, Matthew J, Lustman, Patrick J, Norman, Sonya B, Salas, Joanne, Scherrer, Jeffrey F, Schneider, F. David, Schnurr, Paula P, Tuerk, Peter, van den Berk-Clark, Carissa   +10 more
core   +1 more source

Impact of cyclooxygenase inhibitors in the Women's Health Initiative hormone trials: secondary analysis of a randomized trial. [PDF]

, 2006
OBJECTIVES: We evaluated the hypothesis that cyclooxygenase (COX) inhibitor use might have counteracted a beneficial effect of postmenopausal hormone therapy, and account for the absence of cardioprotection in the Women's Health Initiative hormone trials.
Choe, John H, Hsia, Judith, Kuller, Lewis, Langer, Robert D, Limacher, Marian, Manson, Joann E, O'Sullivan, Mary Jo, Oberman, Albert, Ockene, Judith, Pettinger, Mary, Robinson, Jennifer G, Women's Health Initiative Research,   +11 more
core   +3 more sources

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

Molecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou, Aliki Ntzifa, Victoria Tserpeli, Ioanna Balgkouranidou, Alkistis Papatheodoridi, Evangelia Razis, Helena Linardou, Christos Papadimitriou, Amanda Psyrri, Flora Zagouri, Stylianos Kakolyris, Evi Lianidou   +11 more
wiley   +1 more source

Association of Obstructive Sleep Apnea With Cardiovascular Outcomes in Patients With Acute Coronary Syndrome. [PDF]

, 2019
Background The prognostic significance of obstructive sleep apnea ( OSA ) in patients with acute coronary syndrome ( ACS ) in the contemporary era is unclear.
Fan, Jingyao, Ma, Xin-Liang, Nie, Shaoping, Somers, Virend K., Wang, Xiao, Wei, Yongxiang   +5 more
core   +1 more source

An overall strategy based on regression models to estimate relative survival and model the effects of prognostic factors in cancer survival studies.

, 2007
Relative survival provides a measure of the proportion of patients dying from the disease under study without requiring the knowledge of the cause of death.
Belot, A, Bossard, N, Estève, J, French network of cancer registries FRANCIM, Remontet, L   +4 more
core   +1 more source