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Children chronically infected with hepatitis B virus (HBV) are at high risk of progressive liver disease. However, no treatment is available that is consistently effective in curing chronic hepatitis B (CHB) in children. Improved understanding of the natural course of disease is warranted.
Winther, Thilde Nordmann +4 more
openaire +5 more sources
Correlations of HBV Genotypes, Mutations Affecting HBeAg Expression and HBeAg/ anti-HBe Status in HBV Carriers [PDF]
This study was carried out to determine the effects of hepatitis B virus genotypes, core promoter mutations (A1762G1764-->T1762A1764) as well as precore stop codon mutations (TGG-->TAG) on HBeAg expression and HBeAg/ anti-HBe status. Study was also performed on the effects of codon 15 variants (C1858/ T1858) on the predisposition of precore stop codon ...
Chee Kent, Lim +6 more
openaire +2 more sources
The Role of Quantitative HBsAg Levels in Chronic Hepatitis B Infection
Introduction: Chronic hepatitis B (CHB) infection is essential for patient management, including treatment and follow-up. Therefore, quantitative hepatitis B surface antigen (qHBsAg) may help physicians identify the stages of hepatitis B virus (HBV ...
Merve Kılıç Tekin +2 more
doaj +1 more source
Is the function of the HBeAg really unknown?
The immune response to the hepatitis B virus (HBV) vaccine in newborns of hepatitis B e antigen (HBeAg)-positive or HBeAg-negative mothers is the subject of Huang et al. The authors report no correlation between the HBeAg status of the mothers/cord blood
David R. Milich
doaj +1 more source
Viral Biomarkers in Chronic HBeAg Negative HBV Infection [PDF]
Viral biomarkers are important tools for monitoring chronic hepatitis B virus (HBV) hepatitis B early antigen (HBeAg) negative infection, both in its natural course as well as during and after treatment. The biomarkers consist of antibodies against viral epitopes, viral proteins, and molecular surrogate markers of the quantity and transcriptional ...
Hadziyannis, E., Laras, A.
openaire +3 more sources
Abstract Background Previous studies have indicated that HBV pregenome RNA (HBV pgRNA) could predict HBeAg seroconversion among the chronic hapatitis B (CHB) patients treated with pegylated interferon (Peg-IFN) or nucleos(t)ide analogues (NAs).
Guangjun Song +6 more
openaire +3 more sources
Summary: Background & Aims: We aimed to investigate how viral quasispecies of the HBV whole genome evolves and diversifies in response to HBeAg seroconversion and viral control utilising next-generation sequencing (NGS).
Su-Ru Lin +16 more
doaj +1 more source
Comparison of evolutionary patterns of different HBeAg status in HBV genotype B and C
The aim of this work was to investigate the different evolutionary patterns between HBeAg(+) and HBeAg(-) status of genotype B and genotype C of Hepatitis B virus (HBV).
Cai Ying +3 more
doaj +1 more source
Different interventional criteria for chronic hepatitis B pregnant women with HBeAg(+) or HBeAg(-)
The seroprevalence of hepatitis B virus (HBV) and its impact on pregnancy outcomes of women from Shaanxi Province (China) was assessed. Risk factors for mother-to-child transmission (MTCT) were evaluated based on HBV-related seroprevalence data.Viral markers and biochemical parameters were assessed in HBsAg-positive mothers and their infants out of 13 ...
Chen, Tianyan +13 more
openaire +2 more sources
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu +5 more
wiley +1 more source

