Results 191 to 200 of about 6,219 (219)

TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs [PDF]

Frontiers in Cell and Developmental Biology, 2021
Dehydroepiandrosterone (DHEA) has been revealed to implicate in facilitating osteoblast differentiation of human bone marrow mesenchymal stem cells (hBMSCs) and inhibiting osteoporosis (OP). However, the underlying molecular mechanism remains largely unknown.
Qingjun Wei
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HAMSCs/HBMSCs coculture system ameliorates osteogenesis and angiogenesis against glucolipotoxicity

Biochimie, 2018
Osteoporosis and vascular lesions induced by glucolipotoxicity are common complications of diabetes mellitus (DM). In order to deal with these complications, we designed a new therapeutic strategy, i.e. coculture system containing human amnion-derived mesenchymal stem cells (HAMSCs) and human bone marrow mesenchymal stem cells (HBMSCs).
Chunli, Zhang, Yifei, Du, Hua, Yuan, Fei, Jiang, Ming, Shen, Yuli, Wang, Ruixia, Wang   +6 more
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Chitosan/hBMSC-ECM biomimetic nerve grafts containing orienting microchannels for peripheral nerve regeneration

Biomaterials Advances, 2023
Bone marrow mesenchymal stem cell extracellular matrix (BMSC-ECM) can promote peripheral nerve regeneration, and microphysical orientation is essential for peripheral nerve regeneration. In this study, human-derived BMSC-ECM (hBMSC-ECM) and microchannels were introduced into chitosan-based nerve grafts (OCS/ECM) to construct dual biomimetic nerve ...
Xu, Zhang, Tong, Qi, Yu, Sun, Xiyang, Cheng, Pengxiang, Yang, Xiu, Dai   +5 more
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PAI‐1 transfected‐conditioned media promotes osteogenic differentiation of hBMSCs

Cell Biology International
AbstractReconstruction of injured bone remains challenging in the clinic owing to the lack of suitable bone grafts. The utilization of PAI‐1 transfected‐conditioned media (P‐CM) has demonstrated its ability to facilitate the differentiation process of mesenchymal stem cells (MSCs), potentially serving as a crucial mediator in tissue regeneration.
Zhang Li, Hou Kegui, Wang Piao, Wang Xuejiu, Ki‐Taek Lim, Hexiu Jin   +5 more
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IRX5 suppresses osteogenic differentiation of hBMSCs by inhibiting protein synthesis

Journal of Cellular Physiology
AbstractIn our previous study, IRX5 has been revealed a significant role in adipogenesis of hBMSCs. Considering the expansion of adipose tissue in bone marrow in aged and ovariectomy‐related osteoporosis, the effect of IRX5 on the osteogenesis of BMSCs still needs to be elucidated.
Bulin Jiang, Jiqi Zheng, Hantao Yao, Yake Wang, Fangfang Song, Cui Huang   +5 more
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[Comparison and analysis between CLL-hBMSC and N-hBMSC].

Zhongguo shi yan xue ye xue za zhi, 2014
This study was purpose to compare and analyze the chronic lymphocytic leukemia human bone marrow stromal cells (CLL-hBMSC) and normal hBMSC (N-hBMSC) so as to provide theoretical evidence for establishment of CLL-hBMSC interaction model to imitate CLL microenvironment.
Huan, Wang, Jun, Zhou, Jing-Jing, Xu, Feng, Guo   +3 more
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Promoting Cardiomyogenesis of hBMSC with a Forming Self‐Assembly hBMSC Microtissues/HA‐GRGD/SF‐PCL Cardiac Patch Is Mediated by the Synergistic Functions of HA‐GRGD

Macromolecular Bioscience, 2016
Bone marrow‐derived mesenchymal stem cell microtissues (BMSCMT) enhanced cardiomyogenesis in vitro and cardiac repairs of myocardial infarcted hearts in vivo are documented. Producing human BMSCMT onto patches in vitro for cardiac tissue engineering has not been reported.
Tze-Wen, Chung, Hsin-Yu, Lo, Tzung-Han, Chou, Jan-Hou, Chen, Shoei-Shen, Wang   +4 more
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[Preliminary study on biological printing of hBMSCs].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2010
To establish a two-dimensional biological printing technique of hBMSCs so as to control the cell transfer process and keep cell viability after printing.Bone marrow (5 mL) was obtained from healthy volunteer. The hBMSCs were regularly subcultured to harvest cells at passage 2, which were adjusted to the single cell suspension at a density of 1 x 10(6 ...
Sunxiang, Ma, Gang, Chai, Qihai, Liu, Qingxi, Hu, Guangdong, Zhou, Lei, Cui   +5 more
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TIMP-1 inhibits proliferation and osteogenic differentiation of hBMSCs through Wnt/β-catenin signaling [PDF]

Bioscience Reports, 2019
Abstract The present study aimed to evaluate the effect of tissue inhibitor of metalloproteinase-1 (TIMP-1) on the proliferation and osteogenic differentiation potential of human bone marrow-derived MSCs (hBMSCs). hBMSCs with stable TIMP-1 overexpression or TIMP-1 knockdown were generated.
Dehai Shi
exaly   +3 more sources

hBMSC-TERT in Cutaneous Diabetic Wound—Histological Analysis and Metalloproteinases

Diabetes, 2018
Diabetes (DM) is associated with micro- and macrovascular complications and impaired wound healing which leads to the formation of chronic lesions. Mesenchymal stem cells exert anti-inflammatory and secretory actions and their use in chronic lesions has obtained a high success rate, improving the healing process. In the present study, we have evaluated
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