Results 221 to 230 of about 1,553,868 (271)

Cloned HBV DNA causes hepatitis in chimpanzees

Nature, 1982
Most of our knowledge of the structure and function of the hepatitis B virus (HBV) genome comes from the analysis of the viral DNA sequences cloned in bacteria1–3. Because the physical state of cloned HBV DNA differs from HBV DNA encapsidated in the virion—for example, it lacks the nick-gap structure4, and a covalently linked protein5—the question ...
H, Will, R, Cattaneo, H G, Koch, G, Darai, H, Schaller, H, Schellekens, P M, van Eerd, F, Deinhardt   +7 more
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Studies on the structure of HBV DNA.

Science in China. Series B, Chemistry, life sciences & earth sciences, 1989
The structure of HBV adr NC-1 DNA is analyzed and compared with another five strains of HBV DNAs. Some of the prokaryotic promoter-like sequences, palindrom sequences and ATAA are found. An enhancer core sequence and some other characteristics are also shown.
Qi, ZH, Yan, J, Zhu, QL
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Assessment of a method for detecting serum HBV DNA with HBV DNA probe labelled directly by alkaline phosphatase.

Hepatobiliary & pancreatic diseases international : HBPD INT, 2004
To assess a sensitive and specific technique for detecting serum HBV DNA with an HBV DNA probe labelled directly by alkaline phosphatase (AlkPhos Direc probe).AlkPhos Direc probe was prepared with purified HBV DNA labelled directly by alkaline phosphatase. The probe and chemiluminescent substrate CDP-star for AP were used in hybridization assay.
Ya-Xi, Chen, Ai-Long, Huang, Zhen-Yuan, Qi, You-Lan, Shan, Hang, Sun   +4 more
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An overview of assays for serum HBV DNA.

Clinical laboratory, 2001
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Ho, SKN, Chan, TM
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Mapping of 5′ Ends of Virion-Derived HBV DNA

Virology, 1992
Mapping of the 5' ends of virion-derived hepatitis B virus DNA molecules was carried out after cloning and sequencing linearized genomes made fully double stranded. Of five clones obtained, three of four minus strand termini mapped to the G in position 1826 and one to the T in position 1827.
J A, Saldanha, H, Qiu, H C, Thomas, J, Monjardino   +3 more
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State of HBV DNA in HBsAg‐negative, anti‐HCV‐positive hepatocellular carcinoma: Existence of HBV DNA possibly as nonintegrated form with analysis by Alu‐HBV DNA PCR and conventional HBV PCR

Journal of Medical Virology, 2001
AbstractThe role of hepatitis B virus (HBV) in carcinogenesis of hepatitis B surface antigen (HBsAg)‐negative, anti‐hepatitis C virus (anti‐HCV)‐positive hepatocellular carcinoma (HCC) remains unknown. To investigate the state of HBV DNA in such HCC, HBV DNA was examined by polymerase chain reaction (PCR) between HBV DNA and human Alu sequence (HBV‐Alu
S, Kawai, O, Yokosuka, F, Imazeki, Y, Maru, H, Saisho   +4 more
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Enhancement of immune responses to an HBV DNA vaccine by electroporation

Vaccine, 2006
These studies document the ability of electroporation (EP)-based DNA vaccination to induce multi-specific CTL responses to hepatitis B virus (HBV) DNA vaccination in normal mice and marked immune responses to multivalent HBV DNA immunization in larger animal species.
A, Luxembourg, D, Hannaman, B, Ellefsen, G, Nakamura, R, Bernard   +4 more
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Quantitative detection of serum HBV DNA in Chinese patients

Journal of Viral Hepatitis, 1997
Summary. The relationship between serum hepatitis Be antigen (HBeAg) and serum hepatitis B virus (HBV) DNA determined by two commercially available assays was examined in 345 Chinese patients with chronic HBV infection. HBV DNA was detected by these commercial assays in 85% of the HBeAg‐positive patients.
Lai, CL, Low, BG, Lau, JYN, Wu, PC, Lai, VCH   +4 more
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Electroporation-Mediated HBV DNA Vaccination in Primate Models

2008
Electroporation has been shown to be an effective method to improve the efficiency of gene expression and the immunogenicity of DNA vaccines. To optimize the procedure and test for its efficacy in more clinically relevant large animal models, we studied the effects of electroporation-mediated DNA vaccination with different electro-pulse parameters in ...
Yong-Gang, Zhao, Yuhong, Xu
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Treatment decisions based on HBV DNA

Journal of Viral Hepatitis
AbstractThe most common cause of hepatocellular carcinoma (HCC) worldwide is chronic hepatitis B virus (HBV) infection (CHB). Long‐term suppression of HBV replication by antiviral treatment reduces the risk of HCC and mortality. Nonetheless, only 2.2% of CHB patients globally received the treatment in 2019.
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