Results 131 to 140 of about 333,660 (389)
The paradox of HBV evolution as revealed from a 16th century mummy
PLoS Pathogens, 2018 Hepatitis B virus (HBV) is a ubiquitous viral pathogen associated with large-scale morbidity and mortality in humans. However, there is considerable uncertainty over the time-scale of its origin and evolution. Initial shotgun data from a mid-16th century
Zoe Patterson Ross +10 more
semanticscholar +1 more source
Clinical Pharmacology in Drug Development, EarlyView.Abstract Bepirovirsen, an antisense oligonucleotide in development for the treatment of chronic hepatitis B virus (HBV) infection, is administered from glass vials as a subcutaneous (SC) injection by healthcare professionals (HCPs). A ready‐to‐use prefilled syringe (PFS) assembled with a safety syringe device (SSD) has been developed to make ...
Amir S. Youssef +15 more
wiley +1 more source
Infection and Drug Resistance, 2020 Yuan Nie,* Xizi Deng,* Yun Lan, Linghua Li, Feng Li, Fengyu Hu Research Institute, Guangzhou Eighth People’s Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this ...
Nie Y, Deng X, Lan Y, Li L, Li F, Hu F
doaj
Honour based violence and the multi-agency approach in Nottingham: response of local agencies to honour based violence [PDF]
, 2011 The focus of the research was to gain an understanding of the current levels of HBV in Nottingham and the nature of the multi-agency response. The main aim of the research was to gain an understanding of practitioners' work with a range of issues ...
Gillespie, T +2 more
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Modelling of hydrological response to climate change in glacierized Central Asian catchments [PDF]
, 2007 The arid lowlands of Central Asia are highly dependent on the water supplied by the Tien Shan mountains. Snow and ice storage make large contributions to current runoff, particularly in summer.
Braun, L. N. +3 more
core +1 more source
Recent Update on the Role of Circular RNAs in Hepatocellular Carcinoma
Journal of Hepatocellular Carcinoma, 2021 Abdullah Ely, Kristie Bloom, Mohube Betty Maepa, Patrick Arbuthnot Wits/SAMRC Antiviral Gene Therapy Research Unit, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaCorrespondence: Patrick ...
Ely A, Bloom K, Maepa MB, Arbuthnot P
doaj
Core promoter: A critical region where the hepatitis B virus makes decisions [PDF]
, 2014 The core promoter (CP) of the viral genome plays an important role for hepatitis B virus (HBV) replication as it directs initiation of transcription for the synthesis of both the precore and pregenomic (pg) RNAs.
Quarleri, Jorge Fabian
core +1 more source
Clinics in Liver Disease, 2019 Chronic hepatitis B remains a significant cause of morbidity and mortality worldwide. Most hepatitis B virus (HBV)-infected individuals are neither diagnosed nor treated. In those treated, nucleos(t)ide polymerase inhibitors persistently suppress viremia to the limits of quantitation; however, few achieve a "functional cure," defined as sustained off ...
openaire +3 more sources
Designing a therapeutic hepatitis B vaccine to circumvent immune tolerance
Human Vaccines & Immunotherapeutics, 2020 An effective prophylactic hepatitis B virus (HBV) vaccine has long been available but is ineffective for chronic infection. The primary cause of chronic hepatitis B (CHB) and greatest impediment for a therapeutic vaccine is the direct and indirect ...
DC Whitacre +11 more
doaj +1 more source
Parallel and overlapping Human Immunodeficiency Virus, Hepatitis B and C virus Infections among pregnant women in the Federal Capital Territory, Abuja, Nigeria [PDF]
, 2009 Background: Risk factors that are associated with HIV infection are also associated with HBV and HCV infections in sub-Saharan Africa. The HIV-infected pregnant cohort represents a unique population and infection with the hepatitis virus is considered a ...
Bassey, EB, Moses, AE, Udo, SM, Umo, AN
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