Results 51 to 60 of about 1,553,849 (227)

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

Does pre-liver transplant HBV DNA level affect HBV recurrence or survival in liver transplant recipients receiving HBIg and nucleos(t)ide analogues?

Annals of Hepatology, 2011
Background and Aims. The risk of recurrent hepatitis B virus (HBV) infection and prognosis of liver transplantation in patients with HBV has dramatically changed with the use of prophylaxis including hepatitis B immune globulin (HBIg) and antiviral ...
Isabel Campos-Varela, Lluís Castells, María Buti, Víctor Vargas, Itxarone Bilbao, Francisco Rodríguez-Frías, Rosendo Jardí, Ramón Charco, Jaime Guardia, Rafael Esteban   +9 more
doaj   +1 more source

The TUBA1B–G3BP2 Axis Sustains p65 Transcriptional Activity to Promote Hepatocellular Carcinoma Progression

Advanced Science, EarlyView.
TUBA1B is consistently upregulated in hepatocellular carcinoma and sustains malignant progression by stabilizing G3BP2. By restraining TRIM25‐associated K48‐linked ubiquitination, TUBA1B preserves the G3BP2–IκBα complex and basal NF‐κB/p65 activity. Concurrent TUBA1B/G3BP2 upregulation identifies an aggressive HCC subgroup with enhanced p65 activation ...
Fen Lin, Hechun Lin, Junming Yu, Chao Ge, Lin Mao, Saihua Zhang, Yizi Jin, Yunyu Wu, Taoyang Chen, Jinjun Li, Hong Li   +10 more
wiley   +1 more source

Erratum to 'The management of chronic hepatitis B in the immunocompromised patient: recommendations from a single topic meeting' [J. Clin. Virol. 41 (4) 2008 243-254] [PDF]

, 2008
Patients with chronic hepatitis B virus (HBV) infection have a substantial risk of reactivation and jaundice following the use of immunosuppressant therapy.
Pol, Stanislas, Hayes, Peter C, Mills, Peter R, Carman, William, Mutimer, David, Barclay, Stephen, Benhamou, Yves, Cameron, Sheila   +7 more
core  

Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians. [PDF]

, 2010
BACKGROUND: The prevalence of HIV/hepatitis co-infection in sub-Saharan Africa is not well documented, while both HIV and HBV are endemic in this area.
Jobarteh Modou, Mendy Maimuna, Cotten Matt, Cotten, M, Alabi, A, Tedder, Richard, Sarge-Njie Ramu, Peterson, Ingrid, Whittle, H, Jaye, A, Peterson Ingrid, Richard Tedder, Rowland-Jones, Sarah, Malfroy Marine, Peterson, K, Maimuna Mendy, Jobarteh, Modou, Cotten, Matt, Tedder Richard, Malfroy, M, Peterson, I, Hilton Whittle, Matt Cotten, Sarge-Njie, Ramu, Sarah Rowland-Jones, Ingrid Peterson, Hall, A, Peterson, Kevin, Peterson Kevin, Jaye Assan, Jaye, Assan, Tedder, R, Mendy, Maimuna, Whittle Hilton, Modou Jobarteh, Hall, Andrew, Hall Andrew, Jeng Adam, Alabi, Abraham, Ramu Sarge-Njie, Malfroy, Marine, Mendy, M, Alabi Abraham, Assan Jaye, Whittle, Hilton, Jeng, A, Adam Jeng, Rowland-Jones Sarah, Jobarteh, M, Andrew Hall, Jeng, Adam, Kevin Peterson, Marine Malfroy, Abraham Alabi, Sarge-Njie, R, Rowland-Jones, S   +55 more
core   +1 more source

A General High‐Throughput Mucus Microrheology Platform for Quantitative and Scalable Mucus Phenotyping

Advanced Science, EarlyView.
High‐throughput Differential Dynamic Microscopy measures frequency‐resolved mechanical fingerprints from 3 to 10 μL$\umu{\rm L}$ mucus samples using only a few minutes of operator attention per sample. This automated analysis enables scalable mucus phenotyping for translational research by distinguishing mechanical heterogeneity among donors, disease ...
Feng Ling, Ayşe Tuğçe Şahin, Bernardo Miller Naranjo, Stefano Aime, Doris Roth, Anna Pukaluk, Niels Tepho, Romina Augustin, Benedetta Zampa, Andrea S. Vendrame, Mark‐Christian Klassen, Ellen Emken, Marion Kiechle, Mircea Gabriel Stoleriu, Pontus Mertsch, Ruth Olmer, Yohannes Tesfaigzi, Oliver Lieleg, Janna C. Nawroth   +18 more
wiley   +1 more source

Standardized Hepatitis B Virus RNA Quantification in Untreated and Treated Chronic Patients: a Promising Marker of Infection Follow-Up

Microbiology Spectrum, 2022
The measurement and interpretation of HBV DNA and RNA levels in HBV infected patients treated with antiviral therapy supports the objective of HBV disease management.
Maria Francesca Cortese, Mar Riveiro-Barciela, David Tabernero, Francisco Rodriguez-Algarra, Adriana Palom, Sara Sopena, Ariadna Rando-Segura, Luisa Roade, Alison Kuchta, Roser Ferrer-Costa, Josep Quer, Beatriz Pacin, Marta Vila, Rosario Casillas, Selene Garcia-Garcia, Rafael Esteban, Tomás Pumarola, Maria Buti, Francisco Rodriguez-Frias   +18 more
doaj   +1 more source

The prevalence of occult hepatitis B virus (hbv) infection in a large multi-ethnic haemodialysis cohort. [PDF]

, 2015
Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HBV) infection ...
Labbett, W, Patel, M, O'Riordan, A, Davenport, A, Sowole, L, Haque, T, Cross, J   +6 more
core  

USP4‐Dependent CHAF1B Stabilization Regulates Distinct SETDB1 Ubiquitin States Linked to AKT T308 Signaling and Lipogenic Remodeling in HCC

Advanced Science, EarlyView.
USP4 stabilizes CHAF1B by limiting K48‐linked ubiquitination. Stabilized CHAF1B supports UHRF1‐associated K63‐linked SETDB1 ubiquitination and cytoplasmic redistribution, whereas CHAF1B loss favors VHL‐dependent K11‐associated degradative ubiquitination and proteasomal loss of SETDB1.
Saiyan Bian, Yun Tong, Wenkai Ni, Zhangzhi Tang, Weiting Chen, Kexin Ma, Lihan Jiang, Jiayu Shao, Xuyang He, Wenjie Zheng   +9 more
wiley   +1 more source

The relationship between serum hepatitis B virus DNA level and liver histology in patients with chronic HBV infection. [PDF]

PLoS ONE, 2018
BACKGROUND:There is no consensus regarding the relationship between HBV DNA and liver fibrosis, and the relationship between HBV DNA and the degree of liver cirrhosis has not been reported in patients with chronic HBV infection. METHODS:From January 2011
Changjiang Liu, Li Wang, Huizhong Xie, Liyuan Zhang, Bingshu Wang, Chun Luo, Suiqun Wang, Mingliang Tang, Zhongbiao Fu, Hailan Ruan, Zhengjin Liu, Ling Wei, Wenyi Yi, Yunqian Xie   +13 more
doaj   +1 more source