Results 81 to 90 of about 69,966 (266)
A Serum lncRNA Signature Determines Oncogenic YAP Activity in Cancer Patients
International Journal of Cancer, EarlyView.Long non‐coding RNAs (lncRNAs) signatures are promising cancer biomarkers, since their dysregulation in tumors is reflected in body fluids. In this study, next‐generation sequencing, bioinformatics, and gene expression data were combined to investigate an lncRNA signature linked specifically to the cancer‐promoting YAP in several cancer types ...
Fabian Rose +24 more
wiley +1 more source
Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes
iMeta, EarlyView.Nanopore direct RNA sequencing advances transcriptomics by capturing full‐length transcripts and multiple RNA modifications; this review details its principles, workflows, tools, applications, challenges, and future research potential. Abstract Nanopore direct RNA sequencing (DRS) has transformed transcriptomics by enabling single‐molecule, long‐read ...
Tianyuan Zhang +27 more
wiley +1 more source
, 2012 IL28B polymorphism (IL28Bp) is associated with spontaneous and treatment induced HCV clearance, whereas its role in HBV infection is still debated. We analysed the correlation between IL28Bp and phase and outcome of HBV infection and HBsAg clearance in ...
CHERUBINI, BEATRICE
core
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
, 2013 Serum HBV DNA levels were quantified in 72 consecutive samples with the Abbott Real Time HBV PCR (threshold at 1.7 log IU/mL). HBV target was not detected in 21 patients; viral load was detected in 51 patients, 16 of whom had a viral load greater than 7 ...
Pierre Abgueguen (483490) +9 more
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu +5 more
wiley +1 more source
Occult HBV infection among Egyptian hepatocellular carcinoma patients
Virology Journal, 2011 Background Occult HBV infection accelerates the progression of liver fibrosis, cirrhosis, and finally leading to hepatocellular carcinoma (HCC). This study analyzed the occult HBV-genotypes in HCC patients. Methods To achieve our objective, matched serum
Mansor Tarek M +3 more
doaj +1 more source
Interdisciplinary Medicine, EarlyView.Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu +6 more
wiley +1 more source
, 2008 Patients with chronic hepatitis B virus (HBV) infection have a substantial risk of reactivation and jaundice following the use of immunosuppressant therapy.
Pol, Stanislas +7 more
core
Soluble B7‐H6 as a Novel Diagnostic Biomarker for Post‐Hepatitis B Cirrhosis: A Clinical Value Study
Journal of Clinical Laboratory Analysis, EarlyView.This study investigates the potential of soluble B7‐H6 (sB7‐H6) as a novel diagnostic biomarker for post‐hepatitis B cirrhosis. The infographic visually presents the following key points: (1) Liver Disease Progression: Chronic hepatitis B (CHB) progresses to liver cirrhosis (LC), with serum sB7‐H6 levels increasing stepwise as the disease advances. (2)
Kaiyong Chen +4 more
wiley +1 more source