Results 31 to 40 of about 60,065 (147)

HTLV-1 Alters T Cells for Viral Persistence and Transmission

Frontiers in Microbiology, 2018
Human T-cell leukemia virus type 1 (HTLV-1) was the first retrovirus to be discovered as a causative agent of adult T-cell leukemia-lymphoma (ATL) and chronic inflammatory diseases.
Azusa Tanaka, Masao Matsuoka, Masao Matsuoka   +2 more
doaj   +1 more source

Cytoplasmic Localization of HTLV-1 HBZ Protein: A Biomarker of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). [PDF]

PLoS Neglected Tropical Diseases, 2017
HTLV-1 is the causative agent of a severe form of adult T cell leukemia/Lymphoma (ATL), and of a chronic progressive neuromyelopathy designated HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Marco Baratella, Greta Forlani, Goutham U Raval, Alessandra Tedeschi, Olivier Gout, Antoine Gessain, Giovanna Tosi, Roberto S Accolla   +7 more
doaj   +1 more source

Das Rosetta-Projekt des hbz [PDF]

, 2016
Das Rosetta-Projekt des hbz.
Quast, Andres (Dr.), Schomburg, Silke (Dr.)   +1 more
core   +3 more sources

HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).

PLoS Pathogens, 2016
Human T-cell leukemia virus type 1 (HTLV-1) infects CD4+ T cells and induces proliferation of infected cells in vivo, which leads to the onset of adult T-cell leukemia (ATL) in some infected individuals.
Keiko Yasuma, Jun-ichirou Yasunaga, Keiko Takemoto, Kenji Sugata, Yuichi Mitobe, Norihiro Takenouchi, Masanori Nakagawa, Yutaka Suzuki, Masao Matsuoka   +8 more
doaj   +1 more source

In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Retrovirology, 2009
Background Recently, human T-cell leukemia virus type 1 (HTLV-1) basic leucine zipper factor (HBZ), encoded from a minus strand mRNA was discovered and was suggested to play an important role in adult T cell leukemia (ATL) development.
Saito Kousuke, Yasunaga Jun-ichirou, Satou Yorifumi, Matsuzaki Toshio, Saito Mineki, Arimura Kimiyoshi, Matsuoka Masao, Ohara Yoshiro   +7 more
doaj   +1 more source

The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.

PLoS Pathogens, 2021
Viral infections are known to hijack the transcription and translation of the host cell. However, the extent to which viral proteins coordinate these perturbations remains unclear. Here we used a model system, the human T-cell leukemia virus type 1 (HTLV-
Charlotte Vandermeulen, Tina O'Grady, Jerome Wayet, Bartimee Galvan, Sibusiso Maseko, Majid Cherkaoui, Alice Desbuleux, Georges Coppin, Julien Olivet, Lamya Ben Ameur, Keisuke Kataoka, Seishi Ogawa, Olivier Hermine, Ambroise Marcais, Marc Thiry, Franck Mortreux, Michael A Calderwood, Johan Van Weyenbergh, Jean-Marie Peloponese, Benoit Charloteaux, Anne Van den Broeke, David E Hill, Marc Vidal, Franck Dequiedt, Jean-Claude Twizere   +24 more
doaj   +1 more source

Transparent Topological Meta‐Diplexer via Tightly Confined Valley Surface States

Advanced Science, EarlyView.
An optically transparent topological metasurface supporting tightly confined valley surface states enables robust and flexible wave routing in an ultrathin platform. A compact transparent meta‐diplexer with spatially and spectrally separated channels is realized, while communication experiments verify high‐fidelity signal transmission, opening new ...
Sijie Li, Ping Li, Zhihao Lan, Yin Li, Hang Wong, Menglin L.N. Chen   +5 more
wiley   +1 more source

hbz, institution, services and beyond [PDF]

, 2012
Presentation with the title "hbz, institution, services and beyond" within the scope of the CALIS Delegation from China - Springer study ...
Heyder, Nannette
core   +3 more sources

Preclinical assessment of an anti-HTLV-1 heterologous DNA/MVA vaccine protocol expressing a multiepitope HBZ protein

Virology Journal, 2023
Background Human T-lymphotropic virus 1 (HTLV-1) is associated with the development of several pathologies and chronic infection in humans. The inefficiency of the available treatments and the challenge in developing a protective vaccine highlight the ...
D. S. O. Daian e Silva, L. J. Cox, A. S. Rocha, Á. Lopes-Ribeiro, J. P. C. Souza, G. M. Franco, J. L. C. Prado, T. A. Pereira-Santos, M. L. Martins, J. G. A. Coelho-dos-Reis, T. M. Gomes-de-Pinho, F. G. Da Fonseca, E. F. Barbosa-Stancioli   +12 more
doaj   +1 more source

Targeted Interventions in HAM/TSP: Emerging Therapies and Future Directions – A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aim Human T‐Lymphotropic virus type 1 (HTLV‐1) infection can lead to HTLV‐1‐associated myelopathy/tropical spastic paraparesis (HAM/TSP), a debilitating chronic neurological disease characterized by progressive lower limb spasticity and autonomic dysfunction.
Meygol Mirzaei Rezaei, Mahdi Khosravi Nia, Kasra Allaei Rouzbahani, Maryam Kazemi, Negar Asghari Hosori, Mehdi Norouzi, Farzaneh Sotoudegan, Narges Eslami, Negar Ariamand, Vahid Shahnavaz, Arash Letafati, Sayed‑Hamidreza Mozhgani   +11 more
wiley   +1 more source