Results 51 to 60 of about 60,065 (147)

Plone im hbz - Corporate Website und DiPP [PDF]

, 2007
Vortrag im Rahmen der Veranstaltung ZonePlone im November 2007 mit dem Titel "Plone im hbz - Corporate Website und DiPP" von Dr.
Reimer, Peter (Dr.)
core   +3 more sources

Regulation of human T-lymphotropic virus type I latency and reactivation by HBZ and Rex.

PLoS Pathogens, 2014
Human T lymphotropic virus type I (HTLV-I) infection is largely latent in infected persons. How HTLV-1 establishes latency and reactivates is unclear. Here we show that most HTLV-1-infected HeLa cells become senescent. By contrast, when NF-κB activity is
Subha Philip, Muhammad Atif Zahoor, Huijun Zhi, Yik-Khuan Ho, Chou-Zen Giam   +4 more
doaj   +1 more source

CARD11 mutation and HBZ expression induce lymphoproliferative disease and adult T-cell leukemia/lymphoma

Communications Biology, 2022
The oncogenic ability of mutant CARD11 (E626K), one of most frequently mutated genes in adult T-cell leukemia and its cooperative effect with HBZ expression, using the CD4 promoter-driven HBZ transgenic mouse model, is investigated.
Takuro Kameda, Kotaro Shide, Ayako Kamiunten, Yasunori Kogure, Daisuke Morishita, Junji Koya, Yuki Tahira, Keiichi Akizuki, Takako Yokomizo-Nakano, Sho Kubota, Kosuke Marutsuka, Masaaki Sekine, Tomonori Hidaka, Yoko Kubuki, Yuichi Kitai, Tadashi Matsuda, Akinori Yoda, Takayuki Ohshima, Midori Sugiyama, Goro Sashida, Keisuke Kataoka, Seishi Ogawa, Kazuya Shimoda   +22 more
doaj   +1 more source

HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo.

PLoS Pathogens, 2011
Human T-cell leukemia virus type 1 (HTLV-1) is the causal agent of a neoplastic disease of CD4+ T cells, adult T-cell leukemia (ATL), and inflammatory diseases including HTLV-1 associated myelopathy/tropical spastic paraparesis, dermatitis, and ...
Yorifumi Satou, Jun-Ichirou Yasunaga, Tiejun Zhao, Mika Yoshida, Paola Miyazato, Ken Takai, Kei Shimizu, Koichi Ohshima, Patrick L Green, Naganari Ohkura, Tomoyuki Yamaguchi, Masahiro Ono, Shimon Sakaguchi, Masao Matsuoka   +13 more
doaj   +1 more source

Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies

MedComm, Volume 7, Issue 5, May 2026.
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang, Zengkan Du, Ping Lu, Aimin Jiang, Yadong Guo, Yawei Liu, Zhijing Song, Bing Dai, Wangzheqi Zhang   +8 more
wiley   +1 more source

HTLV‐1 Tax Reshapes the DNA‐Binding Pattern of Transcription Factor IRF4 and Disrupts Host Gene Regulation

Cancer Science, Volume 117, Issue 5, Page 1497-1509, May 2026.
Proteomic mapping of Tax complexes in HTLV‐1–infected T‐cells identified IRF4 as a Tax interactor. Chromatin profiling showed Tax reprograms IRF4 occupancy with H3K27ac gains at super‐enhancers; Tax–IRF4 co‐expression altered chromatin accessibility and transcription, and ATL‐associated IRF4 mutants partially phenocopied these changes. ABSTRACT Human T‐
Shu Tosaka, Jun Mizuike, Motomu Yano, Kaoru Uchimaru, Makoto Yamagishi   +4 more
wiley   +1 more source

OLE Evaluierungsprojekt von hbz und GBV - Projektstand [PDF]

, 2015
Präsentation zu dem Thema "OLE Evaluierungsprojekt von hbz und GBV - Projektstand" für Kuali OLE Workshop in Köln am 15.
Schweitzer, Roswitha
core   +3 more sources

ERMS - Das Lizenzverwaltungstool der hbz-Konsortialstelle [PDF]

, 2013
Präsentation der Digitalen Inhalte zum Thema "ERMS - Das Lizenzverwaltungstool der hbz-Konsortialstelle" im Rahmen des 5.
Selbach, Michaela
core   +3 more sources

Fe–Mn Crust δ98Mo Decline Records Tectonic Forcing on Marine Oxide Sink Reduction During the Early Eocene–Early Oligocene

Geophysical Research Letters, Volume 53, Issue 7, 16 April 2026.
Abstract S, Tl, and W isotope records document pronounced early Eocene shifts in marine redox, yet the absence of a Mo isotope record obscures its progression. Here, we present ∼80 Myr Mo–Os–Be–Nd isotope profiles from a Northwest Pacific hydrogenetic Fe–Mn crust, revealing a systematic δ98Mo decline from −0.24‰ (early Eocene) to −0.83‰ (early ...
Limin Zhang, Jiangbo Ren, Hongjin Chen, Haozhe Wang, Zhen Sun, Yong Yang, Huodai Zhang, Zhenquan Wei, Lixue Zhang, Yingzhi Ren, Gaowen He   +10 more
wiley   +1 more source

Single-cell heterogeneity and cell-cycle-related viral gene bursts in the human leukaemia virus HTLV-1 [version 2; referees: 2 approved, 1 approved with reservations]

Wellcome Open Research, 2017
Background: The human leukaemia virus HTLV-1 expresses essential accessory genes that manipulate the expression, splicing and transport of viral mRNAs.  Two of these genes, tax and hbz, also promote proliferation of the infected cell, and both genes are ...
Martin R Billman, David Rueda, Charles R M Bangham   +2 more
doaj   +1 more source