Viral Oncogenesis: Synergistic Role of Genome Integration and Persistence [PDF]
VirusesPersistence is a strategy used by many viruses to evade eradication by the immune system, ensuring their permanence and transmission within the host and optimizing viral fitness. During persistence, viruses can trigger various phenomena, including target
Simone La Frazia +3 more
doaj +4 more sources
Deciphering the roles of myeloid derived suppressor cells in viral oncogenesis [PDF]
Frontiers in Immunology, 2023 Myeloid derived suppressor cells (MDSCs) are a heterogenous population of myeloid cells derived from monocyte and granulocyte precursors. They are pathologically expanded in conditions of ongoing inflammation where they function to suppress both innate ...
Claire Shannon-Lowe
exaly +4 more sources
Hot and Cold HCC: Uncoupling Viral Oncogenesis and Therapy [PDF]
VirusesHepatocellular carcinoma (HCC) is rising in incidence globally. It is the sixth most common cancer and the third leading cause of cancer-related mortality worldwide.
Laura Sneller +3 more
doaj +3 more sources
Recent Updates on Viral Oncogenesis: Available Preventive and Therapeutic Entities [PDF]
Molecular Pharmaceutics, 2023 Funding Information: Any organizations for this work supported no funding. Publisher Copyright: © 2023 The Authors. Published by American Chemical SocietyHuman viral oncogenesis is a complex phenomenon and a major contributor to the global cancer burden.
Piyush Kumar Gupta +1 more
exaly +3 more sources
The eEF1A Proteins: At the Crossroads of Oncogenesis, Apoptosis, and Viral Infections [PDF]
Frontiers in Oncology, 2015 Eukaryotic translation elongation factors 1 alpha, eEF1A1 and eEF1A2, are not only translation factors, but also pleiotropic proteins that are highly expressed in human tumors, including breast cancer, ovarian cancer and lung cancer.
Wasim Abbas, Georges Herbein
exaly +4 more sources
Viral oncogenesis in cancer: from mechanisms to therapeutics [PDF]
Signal Transduction and Targeted TherapyThe year 2024 marks the 60th anniversary of the discovery of the Epstein-Barr virus (EBV), the first virus confirmed to cause human cancer. Viral infections significantly contribute to the global cancer burden, with seven known Group 1 oncogenic viruses,
Qing Xiao +9 more
doaj +2 more sources
HIV and Cancer: Insights into Viral-Mediated Oncogenesis and Immunosuppression [PDF]
PathogensBackground: People living with HIV (PLWH) have a substantially increased risk of both AIDS-defining cancers (ADCs) and non-AIDS-defining cancers (NADCs), which remain a major cause of morbidity despite effective antiretroviral therapy (ART); this review ...
Angioletta Lasagna +7 more
doaj +2 more sources
In Vitro Studies of Pegylated Magnetite Nanoparticles in a Cellular Model of Viral Oncogenesis: Initial Studies to Evaluate Their Potential as a Future Theranostic Tool [PDF]
Pharmaceutics, 2023 Veronica Gonzalez-Pardo +1 more
exaly +2 more sources
HBZ and its roles in HTLV-1 oncogenesis
Frontiers in Microbiology, 2012 Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL). The minus strand of HTLV-1 provirus encodes a bZIP protein donated as HTLV-1 bZIP factor (HBZ).
Tiejun Zhao
exaly +3 more sources
Molecular mechanisms of viral oncogenesis in humans [PDF]
Nature Reviews Microbiology, 2018 Nathan Krump, Jianxin You
exaly +2 more sources