Results 21 to 30 of about 597,555 (197)
Vaccines, 2020 Herpesvirus of turkeys (HVT), used originally as a vaccine against Marek’s disease (MD), has recently been shown to be a highly effective viral vector for generation of recombinant vaccines that deliver protective antigens of other avian pathogens.
Na Tang +6 more
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Molecular mimicry and cancer vaccine development
Molecular Cancer, 2023 Background The development of cancer immunotherapeutic strategies relies on the identification and validation of optimal target tumor antigens, which should be tumor-specific as well as able to elicit a swift and potent anti-tumor immune response.
Maria Tagliamonte +6 more
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A retrospective investigation on canine papillomavirus 1 (CPV1) in oral oncogenesis reveals dogs are not a suitable animal model for high-risk HPV-induced oral cancer. [PDF]
PLoS ONE, 2014 CPV1 (also called COPV) is a papillomavirus responsible for oral papillomatosis in young dogs. The involvement of this viral type in oral oncogenesis has been hypothesized in oral squamous cell carcinomas (SCCs), but has never been investigated in other ...
Ilaria Porcellato +6 more
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iScience, 2021 Summary: The role of oncoviral genotype and co-infection driving oncogenesis remains unclear. We have developed a scalable, high throughput tool for sensitive and precise oncoviral genotype deconvolution. Using tumor RNA sequencing data, we applied it to
Adrian Bubie +6 more
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Viruses, 2020 Marek’s disease is a major scourge challenging poultry health worldwide. It is caused by the highly contagious Marek’s disease virus (MDV), an alphaherpesvirus.
Yashar Sadigh +4 more
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Journal of Translational Medicine, 2021 The host’s immune system may be primed against antigens during the lifetime (e.g. microorganisms antigens—MoAs), and swiftly recalled upon growth of a tumor expressing antigens similar in sequence and structure.
Angela Mauriello +9 more
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Insight into Oncogenic Viral Pathways as Drivers of Viral Cancers: Implication for Effective Therapy
Current Oncology, 2023 As per a recent study conducted by the WHO, 15.4% of all cancers are caused by infectious agents of various categories, and more than 10% of them are attributed to viruses.
Ahmed M. E. Elkhalifa +11 more
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Effect of immunization with fetal cells on adenovirus-12 oncogenesis [PDF]
, 1974 The effect of immunization with hamster fetal cells on the tumor induction by adnovirus type 12 was studied by in vivo and in vitro. The immunization with lO-day old fetal cells showed a recognizable inhibition on the tumor induction by adenovirus type ...
Abe, Shinji
core +1 more source
Degradation of Human PDZ-Proteins by Human Alphapapillomaviruses Represents an Evolutionary Adaptation to a Novel Cellular Niche. [PDF]
PLoS Pathogens, 2015 In order to complete their life cycle, papillomaviruses have evolved to manipulate a plethora of cellular pathways. The products of the human Alphapapillomavirus E6 proteins specifically interact with and target PDZ containing proteins for degradation ...
Koenraad Van Doorslaer +3 more
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Antigenic molecular mimicry in viral-mediated protection from cancer: the HIV case
Journal of Translational Medicine, 2022 Background People living with HIV/AIDS (PLWHA) show a reduced incidence for three cancer types, namely breast, prostate and colon cancers. In the present study, we assessed whether a molecular mimicry between HIV epitopes and tumor associated antigens ...
Carmen Manolio +10 more
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