Results 11 to 20 of about 597,555 (197)

Human Viral Oncogenesis: A Cancer Hallmarks Analysis [PDF]

open access: yesCell Host and Microbe, 2014
Approximately 12% of all human cancers are caused by oncoviruses. Human viral oncogenesis is complex, and only a small percentage of the infected individuals develop cancer, often many years to decades after the initial infection.
Mark Feitelson   +2 more
exaly   +4 more sources

microRNAs in viral oncogenesis

open access: yesRetrovirology, 2007
MicroRNAs are a recently discovered class of small noncoding functional RNAs. These molecules mediate post-transcriptional regulation of gene expression in a sequence specific manner.
Jadhav Vaibhav, Scaria Vinod
doaj   +2 more sources

Ubiquitin-Mediated Effects on Oncogenesis during EBV and KSHV Infection

open access: yesViruses
The Herpesviridae include the Epstein–Barr Virus (EBV) and the Kaposi Sarcoma-associated Herpesvirus (KSHV), both of which are oncogenic gamma-herpesviruses. These viruses manipulate host cellular mechanisms, including through ubiquitin-mediated pathways,
Rachel Mund, Christopher B. Whitehurst
doaj   +2 more sources

Modelling the evolution of viral oncogenesis. [PDF]

open access: yesPhilos Trans R Soc Lond B Biol Sci, 2019
International audienceMost human oncogenic viruses share several characteristics, such as being DNA viruses, having long (co)evolutionary histories with their hosts and causing either latent or chronic infections.
Murall CL, Alizon S.
europepmc   +2 more sources

Non-canonical WNT/PCP signalling in cancer: Fzd6 takes centre stage. [PDF]

open access: yes, 2017
Frizzled receptors are the mediators of the wnt canonical and non-canonical pathways, which play fundamental roles in cell differentiation and organism development.
corda, G
core   +5 more sources

V5 and GFP Tagging of Viral Gene pp38 of Marek’s Disease Vaccine Strain CVI988 Using CRISPR/Cas9 Editing

open access: yesViruses, 2022
Marek’s disease virus (MDV) is a member of alphaherpesviruses associated with Marek’s disease, a highly contagious neoplastic disease in chickens. The availability of the complete sequence of the viral genome allowed for the identification of major genes
Weicheng Li   +4 more
doaj   +1 more source

CRISPR-Mediated Gene Activation (CRISPRa) of pp38/pp24 Orchestrates Events Triggering Lytic Infection in Marek’s Disease Virus-Transformed Cell Lines

open access: yesMicroorganisms, 2021
Marek’s disease (MD) is an immunosuppressive and highly contagious lymphoproliferative disease caused by Marek’s disease virus (MDV) in poultry. Lymphoblastoid cell lines (LCLs) generated ex vivo from MD lymphomas are considered excellent models to study
Poornima Roy   +3 more
doaj   +1 more source

Endolysosomal trafficking of viral G protein-coupled receptor functions in innate immunity and control of viral oncogenesis [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
Govind Bhagat   +2 more
exaly   +2 more sources

A Distinct Anti-EBV DNase Profile in Patients with Undifferentiated Nasopharyngeal Carcinoma Compared to Classical Antigens

open access: yesViruses, 2023
Nasopharyngeal cancer (NPC) is a prevalent type of cancer that often takes the form of undifferentiated carcinoma in the Maghreb region. It affects people of all ages.
Hamid Melouli   +8 more
doaj   +1 more source

Rapid, Sensitive, and Species-Specific Detection of Conventional and Recombinant Herpesvirus of Turkeys Vaccines Using Loop-Mediated Isothermal Amplification Coupled With a Lateral Flow Device Readout

open access: yesFrontiers in Veterinary Science, 2022
Marek's disease, an economically important disease of chickens caused by virulent serotype 1 strains of the Mardivirus Marek's disease virus (MDV-1), is effectively controlled in the field by live attenuated vaccine viruses including herpesvirus of ...
Giulia Mescolini   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy