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Carbonic anhydrase inhibitors:in vitroinhibition of α isoforms (hCA I, hCA II, bCA III, hCA IV) by flavonoids [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry, 2011
A series of flavonoids, such as quercetin, catechin, apigenin, luteolin, morin, were investigated for their inhibitory effects against the metalloenzyme carbonic anhydrase (CA). The compounds were tested against four α-CA isozymes purified from human and bovine (hCA I, hCA II, bCA III, hCA IV) tissues.
Derya Ekinci +4 more
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Building HCA Bridges

HCA Healthcare Journal of Medicine, 2022
Description On June 28, 2021, the incoming residents reported for their first day of orientation at HCA Florida Westside Hospital (HFWH). This GME program is a joint venture and requires the same level of commitment from HCA Florida Northwest Hospital (HFNWH).
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New anticancer drug candidates sulfonamides as selective hCA IX or hCA XII inhibitors

Bioorganic Chemistry, 2018
In this study, new 4-[3-(aryl)-5-substitutedphenyl-4,5-dihydro-1H-pyrazole-1-yl]benzensulfonamides (19-36) were synthesized and evaluated their cytotoxic/anticancer and CA inhibitory effects. According to results obtained, the compounds 34 (4-[5-(2,3,4-trimethoxyphenyl)-3-(thiophen-2-yl)-4,5-dihydro-1H-pyrazole-1-yl] benzensulfonamide, Potency ...
Gul H. I. +8 more
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Design of Crashworthy Structures with Controlled Behavior in HCA Framework

, 2022
Punit Bandi
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Pmu1a, a novel spider toxin with dual inhibitory activity at pain targets hNa _V 1.7 and hCa _V 3 voltage‐gated channels [PDF]