Results 51 to 60 of about 86,186 (285)

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis. [PDF]

, 2016
Colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer-related mortality. Observed during CRC tumorigenesis is loss of post-transcriptional regulation of tumor-promoting genes such as COX-2, TNFα and VEGF. Overexpression of
Aguado, Andrea, Anant, Shrikant, Blanco, Fernando F., Brody, Jonathan R., Dixon, Dan A., Meisner-Kober, Nicole, Padhye, Subhash, Preet, Ranjan, Stevens, Laura E., Vishwakarma, Vikalp, Vyas, Alok, Weir, Scott J., Xu, Liang   +12 more
core   +2 more sources

High‐Resolution Multiplexed Sequencing of Single‐Cell Full‐length Transcriptome Via Combinational Barcoded Tn5 Transposon Insertion

Advanced Science, EarlyView.
CBTi‐seq is reported, leveraging Tn5 transposase‐mediated molecular assembly of combinatorial barcodes and UMIs for high‐resolution multiplexed sequencing of the full‐length transcriptome in single cells. This approach achieves molecular resolution by end‐to‐end sequencing, enabling reconstruction of splice variants and accurate quantification of ...
Liyong He, Kaitong Dang, Qian Sun, Wenjia Wang, Wenbo Li, Wenyi Zhang, Kaiqiang Ye, Handong Wang, Zhengyue Li, Yan Guo, Zheng Li, Chencheng Yao, Peng Li, Yan Huang, Xiangwei Zhao   +14 more
wiley   +1 more source

Optical phase synchronization in coherent optical beamformers for phased array receive antennas [PDF]

, 2009
An optical phase synchronization system using a power feedback loop technique is experimentally demonstrated. The system allows coherent combining of signals modulated on the same optical carrier in a hybrid optical beam forming system ...
Burla, M., Etten, W. van, Garcia-Garcia, A., Khan, M.R.H., Marpaung, D.A.I., Meijerink, A., Roeloffzen, C.G.H., Zhuang, L.   +7 more
core   +3 more sources

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Harnessing Machine Learning and Deep Learning Approaches for Laser‐Induced Breakdown Spectroscopy Data Analysis: A Comprehensive Review

Analysis &Sensing, EarlyView.
Laser‐induced breakdown spectroscopy (LIBS), an atomic emission technique, is widely applied in fields like geology and biology. This rapid elemental analysis method leverages computational tools to boost precision and speed up data processing. This review explores machine learning and deep learning methods for analyzing LIBS spectral data, tackling ...
Pegah Dehbozorgi, Ludovic Duponchel, Vincent Motto‐Ros, Thomas Bocklitz   +3 more
wiley   +1 more source

Geographical variation in the clinical profile of patients with Candida auris

Antimicrobial Stewardship & Healthcare Epidemiology
Objective: To describe Candida auris infections from two different geographical regions within a large health-system, both of which have experienced a significant increase in the occurrence of C. auris.
Taylor Schieber, Kaleb Roemer, Kenneth Sands, Nickie Greer, Julia Moody, Troy Watson, Adam Hasse   +6 more
doaj   +1 more source

Morphological separation of the Central European Trochosa females (Araneae, Lycosidae) [PDF]

, 2009
Adult females of the five Central European wolf spiders Trochosa hispanica Simon, 1870, T. robusta (Simon, 1876), T. ruricola (De Geer, 1778), T. spinipalpis (F. O. P.-Cambridge, 1895), and T. terricola Thorell, 1856 were morphologically analysed.
Hepner, Martin, Milasowszky, Norbert
core  

Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk, Neslihan Balci, Osman Nuri Aslan, Erbay Kalay   +3 more
wiley   +1 more source

Applications of Synthetic Hybrid-Scale Fiber Matrix in Head and Neck Reconstruction: A Case Series

Case Reports in Oncology
Introduction: Patients with head and neck cancer often necessitate complex reconstructions, considering both functional and esthetic concerns. Reconstructions are further complicated by previous radiation therapy and patient co-morbidities, which impair ...
Peter Horwich, Shanmugappiriya Sivarajah, David Neskey, Joshua Hornig   +3 more
doaj   +1 more source

Application of chemometric analysis using physicochemical and chromatographic data to differentiate the origin of plant protection products containing trinexapac-ethyl [PDF]

Journal of Plant Protection Research
The European market for plant protection products (PPPs) faces significant challenges related to counterfeit and substandard PPPs, posing threats to sustainable agriculture and food safety. This study explored the application of chemometric methods based
Patrycja Marczewska, Joanna Rolnik, Tomasz Stobiecki   +2 more
doaj   +1 more source