Results 251 to 260 of about 305,562 (334)

CRISPR Screens Identify PIK3C2A as a Novel Mediator of EGFR Inhibitor Resistance in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is a malignancy with poor prognosis and survival. While epidermal growth factor receptor (EGFR) is a known driver of HNSCC, EGFR inhibitors show limited efficacy as monotherapies, suggesting that effective combination therapies are needed.
Jiayu Wang, Megan L. Ludwig, Aditi Kulkarni, Andrew C. Birkeland, Nicole L. Michmerhuizen, Elizabeth Gensterblum‐Miller, Jingyi Zhai, Hui Jiang, Paul Swiecicki, Marisa Buchakjian, Molly Heft Neal, Steven B. Chinn, Matthew E. Spector, J. Chad Brenner   +13 more
wiley   +1 more source

A novel scoring system to identify patients at low risk for hepatocellular carcinoma five years after DAA-Induced sustained virological response: a retrospective cohort study. [PDF]

BMC Gastroenterol
Fujii H, Nishimura T, Kimura H, Mitsumoto Y, Shima T, Seko Y, Moriguchi M, Kataoka S, Tanaka S, Ishikawa H, Takami S, Nagao Y, Umemura A, Itoh Y, Yamaguchi K.   +14 more
europepmc   +1 more source

Oncofetal dual‑specificity phosphatase 9 drives stem-like properties through ERK1/2-PPARG-SCD axis-mediated lipid metabolism in hepatocellular carcinoma. [PDF]

Clin Transl Med
Peng W, Huang H, Zhao Y, Zhou Q, Cao M, Liu L, Liang J, Cui H, Chen S, Chen W, Xiong S, Cheng B, Bai S.   +12 more
europepmc   +1 more source

Exploring the Role of Metabolic Hyperferritinaemia (MHF) in Steatotic Liver Disease (SLD) and Hepatocellular Carcinoma (HCC) [PDF]

Nikolaos-Andreas Anastasopoulos, Alexandra Barbouti, Anna Goussia, Dimitrios Christodoulou, Georgios K. Glantzounis   +4 more
openalex   +1 more source

From mechanisms to management: Early detection and improved treatment of MASLD and its related hepatocellular carcinoma. [PDF]

Hepatol Commun
Li D, Zhang X.
europepmc   +1 more source

The impact of single-nucleotide variants of hepatitis B virus and antiviral on liver cancer in gray zone patients. [PDF]

J Biomed Sci
Teng W, Chang TT, Su CW, Xu JH, Hsu CC, Chang YC, Liu WC, Chiou YW, Chang YC, Liang YJ, Wu JC.   +10 more
europepmc   +1 more source

Targeting Treg-fibroblast interaction to enhance immunotherapy in steatotic liver disease-related hepatocellular carcinoma. [PDF]

Gut
Prawira A, Xu H, Mei Y, Leow WQ, Nasir NJM, Reolo MJ, Otsuka M, Rahbari M, Chen Z, Weerasooriya M, Abdullah LB, Wu J, Hazirah SN, Wasser M, Chung A, Goh BK, Chow PK, Albani S, Lee J, Lim TKH, Zhai W, Dan YY, Goh GB, Heikenwälder MF, Zhang Y, Dasgupta R, Tai WMD, Liu H, Chen J, Chew V.   +29 more
europepmc   +1 more source

Gut mucosa-associated microbiota signatures in healthy individuals and patients at different stages of liver disease: a pilot study. [PDF]

Gut Pathog
Compare D, Fosso B, Nunziato M, Sgamato C, Di Maggio F, D'Argenio V, Granata I, Zamparelli MS, Lovero D, Casaburi G, Rocco A, Coccoli P, Pesole G, Salvatore F, Nardone G.   +14 more
europepmc   +1 more source

Hepatobiliary phase abbreviated MRI for secondary surveillance after microwave ablation of HCC [PDF]

Pedram Keshavarz, Kevin G. King, Jena Depetris, Matthew Quirk, Tae Won Kang, James Sayre, Myron J. Tong, Justin P. McWilliams, Steven S. Raman, David Lu   +9 more
openalex   +1 more source

Clinicopathologic and prognostic significance of TIAM2 overexpression in resected hepatocellular carcinoma. [PDF]

Future Sci OA
Lu J, Li L, Chen Q, Li B, Ren S, Yuan M, Meng M, Lei J, Bing Y, Wang H, Guo L, Ma Z, Xiu D, Yuan C.   +13 more
europepmc   +1 more source