Results 121 to 130 of about 44,631 (298)

Increased HCMV seroprevalence in patients with hepatocellular carcinoma [PDF]

Virology Journal, 2011
Abstract Background Hepatocellular carcinoma (HCC) is the most common primary liver cancer, usually arising after years of chronic liver inflammation that could result from viral infections such as hepatitis B virus (HBV) and hepatitic C virus (HCV) infections.
Lepiller, Quentin, Tripathy, Manoj, Di Martino, Vincent, Kantelip, Bernadette, Herbein, Georges   +4 more
openaire   +5 more sources

PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway. [PDF]

PLoS Pathogens, 2012
Epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor-α (PDGFRα) were reported to mediate entry of HCMV, including HCMV lab strain AD169.
Adam L Vanarsdall, Todd W Wisner, Hetian Lei, Andrius Kazlauskas, David C Johnson   +4 more
doaj   +1 more source

Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes [PDF]

, 2017
Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plasma membrane of epithelial cells, is required for epithelial polarity.
Adrian J. Giovannone, Alberto Fraile-Ramos, Alenquer M, Barbieri MA, Bezprozvanny I, Bilodeau PS, Breuza L, Britt WJ, Calistri A, Campeau E, Castle AM, Cepeda V, Cepeda V, Chin LS, Clague MJ, Danielsen JM, Delgrossi MH, Dragovic RA, Elena Reales, Fowler KB, Fraile-Ramos A, Fraile-Ramos A, Fujita H, Geng L, Gong Q, Gonzales PA, Guo X, Guo Z, Hackam DJ, Henne WM, Hibi T, Hicke L, Hislop JN, Hong W, Huang F, Huang S, Hurley JH, Jahn R, Kamsteeg EJ, Keith E. Mostov, Kim W, Kwon SH, Kyuuma M, Lakkaraju A, Leung YM, Li X, Liu ST, Low SH, Marchese A, McCullough J, McSharry BP, Meckes DG, Moffat J, Mori Y, Na CH, Naldini L, Naren AP, Olkkonen VM, Ostrowski M, Pallavi Bhattaram, Pawliczek T, Raiborg C, Raiborg C, Ren J, Riento K, Rodriguez-Boulan E, Rothman JE, Sharma N, Shields SB, Shih SC, Simons M, Singer-Lahat D, Somsel Rodman J, Stringer DK, Sudhof TC, Tandon R, ter Beest MB, Thery C, Thomas Weimbs, van Niel G, Weimbs T, Weimbs T, Weimbs T, Wickner W, Wojcikiewicz RJ, Yatsu A, Zerial M   +86 more
core   +3 more sources

The Role of RhoA, RhoB and RhoC GTPases in Cell Morphology, Proliferation and Migration in Human Cytomegalovirus (HCMV) Infected Glioblastoma Cells

Cellular Physiology and Biochemistry, 2016
Background/Aims: Rho GTPases are crucial regulators of the actin cytoskeleton, membrane trafficking and cell signaling and their importance in cell migration and invasion is well- established.
Melpomeni Tseliou, A. Al-Qahtani, S. Alarifi, S. H. Alkahtani, C. Stournaras, G. Sourvinos   +5 more
semanticscholar   +1 more source

Herpesvirus Simplex Virus‐1 Exploits Inflammation to Infect Periodontal Stem Cells and Disrupt Lineage Commitment

Journal of Periodontal Research, EarlyView.
HSV‐1 infects oral mesenchymal stem cells both in vitro and in vivo to dysregulate their lineage commitment. An inflamed gingival environment increases susceptibility to HSV‐1 infection, which further elevates proinflammatory cytokine levels and exacerbates alveolar bone loss.
Araceli Valverde, Raza Ali Naqvi, Yinghua Chen, Alireza Moshaverinia, Anne George, Deepak Shukla, Gloria Martinez, Gabriella Chapa, Salvador Nares, Afsar R. Naqvi   +9 more
wiley   +1 more source

Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells

Frontiers in Immunology, 2017
Human cytomegalovirus (HCMV) primary infection and periodic reactivation of latent virus is generally well controlled by T-cell responses in healthy people.
Sarah E. Jackson, George X. Sedikides, Georgina Okecha, Emma L. Poole, John H. Sinclair, Mark R. Wills   +5 more
doaj   +1 more source

The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2-CH3 Interface of Immunoglobulin G [PDF]

, 2008
Recognition of immunoglobulin G (IgG) by surface receptors for the Fc domain of immunoglobulin G (Fc{gamma}), Fc{gamma}Rs, can trigger both humoral and cellular immune responses.
Bjorkman, Pamela J., Cheung, Evelyn J., Deis Trujillo, Robin, Farley, Alexander H., Hengel, Helmut, Reinhard, Henrike, Sprague, Elizabeth R.   +6 more
core   +3 more sources

HHEX: A Crosstalker between HCMV Infection and Proliferation of VSMCs

Frontiers in Cellular and Infection Microbiology, 2016
Objective: The study was designed to evaluate the role of Human cytomegalovirus (HCMV) infection on homebox (HOX) gene expression and the effects of overexpression of HOX genes on proliferation and apoptosis of vascular smooth muscle cells (VSMCs ...
Lingfang Li, Meitong Liu, Leitao Kang, Yifan Li, Ziyu Dai, B. Wang, Shui-ping Liu, Liyu Chen, Yurong Tan, Guojun Wu   +9 more
semanticscholar   +1 more source

Advances in Cellular Immune Theranostic Approaches for Glioblastoma: Current Trends and Future Directions

Cancer Innovation, Volume 4, Issue 4, August 2025.
Glioblastoma (GBM) remains a highly malignant brain tumor with limited treatment efficacy, driving the need for innovative cellular immune theranostic strategies that integrate diagnostic and therapeutic approaches. Recent advances in cellular immunotherapy for GBM include chimeric antigen receptor (CAR)‐T/NK cells, macrophage‐based therapies ...
Ying Gong, Wanying Lin, Xuechun Fang, Ruyi Zhang, Min Luo, Haoran Wu, Shuai Chu, Chuangkun Li, Yiming Peng, Zhiyan Piao, Siping Wu, Junhao Li, ZongZhong He, Haixia Li, Hongxia Wang   +14 more
wiley   +1 more source

Memory NK cell features exploitable in anticancer immunotherapy [PDF]

, 2019
Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone, Capuano, Cristina, Galandrini, Ricciarda, Palmieri, Gabriella, Pighi, Chiara, Santoni, Angela   +5 more
core   +2 more sources