Results 151 to 160 of about 44,631 (298)

The Core Histone-binding Region of the Murine Cytomegalovirus 89K Immediate Early Protein [PDF]

, 1991
The gene regulatory immediate early protein, pp89, of murine cytomegalovirus interacts with both DNA-associated and isolated histones in vitro. We characterized the histone-binding region of pp89 and its cellular localization during cell division to ...
Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Münch, Konrad   +3 more
core   +1 more source

3D Analysis of HCMV Induced-Nuclear Membrane Structures by FIB/SEM Tomography: Insight into an Unprecedented Membrane Morphology

Viruses, 2015
We show that focused ion beam/scanning electron microscopy (FIB/SEM) tomography is an excellent method to analyze the three-dimensional structure of a fibroblast nucleus infected with human cytomegalovirus (HCMV).
Clarissa Villinger, G. Neusser, C. Kranz, P. Walther, T. Mertens   +4 more
semanticscholar   +1 more source

Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients

Journal of General Virology, 2015
Graft rejection in transplant patients is managed clinically by suppressing T-cell function with immunosuppressive drugs such as prednisolone and methylprednisolone.
Ellen Van Damme, Sarah Sauviller, B. Lau, B. Kesteleyn, P. Griffiths, A. Burroughs, V. Emery, J. Sinclair, M. Van Loock   +8 more
semanticscholar   +1 more source

Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease

Journal of Neuroinflammation, 2015
BackgroundHuman cytomegalovirus (HCMV) is the leading infectious cause of vision loss among congenitally infected children. Retinal pericytes play an essential role in maintaining retinal vascular and endothelial cell proliferation.
Irene Wilkerson, Joshua Laban, Johnathan M Mitchell, N. Sheibani, D. Alcendor   +4 more
semanticscholar   +1 more source

Presentation of three different viral peptides, HTLV-1 Tax, HCMV gB, and influenza virus M1, is determined by common structural features of the HLA-A2.1 molecule. [PDF]

, 1992
Ursula Utz, Sara C. Koenig, J E Coligan, William E. Biddison   +3 more
openalex   +1 more source

IL-12-producing monocytes and HLA-E control HCMV-driven NKG2C+ NK cell expansion.

Journal of Clinical Investigation, 2014
Human cytomegalovirus (HCMV) infection is the most common cause of congenital viral infections and a major source of morbidity and mortality after organ transplantation. NK cells are pivotal effector cells in the innate defense against CMV.
A. Rölle, Julia Pollmann, Eva-Maria Ewen, Vu Thuy Khanh Le, A. Halenius, H. Hengel, A. Cerwenka   +6 more
semanticscholar   +1 more source

Alveolar Macrophages Isolated Directly From Human Cytomegalovirus (HCMV)-Seropositive Individuals Are Sites of HCMV Reactivation In Vivo. [PDF]

, 2015
Human cytomegalovirus (HCMV) causes significant morbidity in the immunocompromised host. Following primary infection, the virus establishes latent infection in progenitor cells of the myeloid lineage.

core   +1 more source

Human cytomegalovirus (HCMV) immediate-early enhancer/promoter specificity during embryogenesis defines target tissues of congenital HCMV infection [PDF]

, 1995
M Koedood, Annette Fichtel, Pascal Meier, Pamela J. Mitchell   +3 more
openalex   +1 more source

Human Cytomegalovirus glycoprotein UL16 causes intracellular sequestration of NKG2D ligands, protecting against NK cell cytotoxicity. [PDF]

, 2003
The activating receptor, NKG2D, is expressed on a variety of immune effector cells and recognizes divergent families of major histocompatibility complex (MHC) class I-related ligands, including the MIC and ULBP proteins.
Chalupny, NJ, Cosman, D, Dosch, S, Dunn, C, Johnson, DC, Sivakumar, PV, Sutherland, CL   +6 more
core  

Value of Different Assays for Detection of Human Cytomegalovirus (HCMV) in Predicting the Development of HCMV Disease in Human Immunodeficiency Virus-Infected Patients [PDF]

, 2000
Brian S. N. Blank, Pieter L. Meenhorst, Jan W. Mulder, Gerrit Jan Weverling, Hein Putter, W. Pauw, Willemien C. van Dijk, Paul H.M. Smits, Sonja Lie-A-Ling, Peter Reiss, Joep M. A. Lange   +10 more
openalex   +1 more source